Biometals. 2005 Apr;18(2):191-7. Related Articles, Links

Characterization of iron compounds in tumour tissue from temporal lobe
epilepsy patients using low temperature magnetic methods.

Brem F, Hirt AM, Simon C, Wieser HG, Dobson J.

ETH-Honggerberg, Institute of Geophysics, CH-8093 Zurich, Switzerland.
brem@mag.ig.erdw.ethz.ch

Excess iron accumulation in the brain has been shown to be related to a
variety of neurodegenerative diseases. However, identification and
characterization of iron compounds in human tissue is difficult because
concentrations are very low. For the first time, a combination of low
temperature magnetic methods was used to characterize iron compounds in
tumour tissue from patients with mesial temporal lobe epilepsy (MTLE).
Induced magnetization as a function of temperature was measured between
2 and 140 K after cooling in zero-field and after cooling in a 50 mT
field. These curves reveal an average blocking temperature for ferritin
of 10 K and an anomaly due to magnetite at 48 K. Hysteresis
measurements at 5 K show a high coercivity phase that is unsaturated at
7 T, which is typical for ferritin. Magnetite concentration was
determined from the saturation remanent magnetization at 77 K.
Hysteresis measurements at various temperatures were used to examine
the magnetic blocking of magnetite and ferritin. Our results
demonstrate that low temperature magnetic measurements provide a useful
and sensitive tool for the characterisation of magnetic iron compounds
in human tissue.

PMID: 15954745 [PubMed - in process]

--------------------------------------------------------------------------------

Who loves ya.
Tom
Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.­com
Man Is A Herbivore!
http://pages.ivillage.com/iron­justice/manisaherbivore
DEAD PEOPLE WALKING
http://pages.ivillage.com/iron­justice/deadpeoplewalking