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Medical Forum / Diseases and Disorders / Alzheimer's / April 2005

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Brain Tests Help Evaluate Mental Condition

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Karen - 24 Apr 2005 18:45 GMT
When my MIL was diagnosed, the neurologist said her MRI showed "classic
brain shrinkage patterns consistent with Alzheimer's".  They had done the
MRI to rule out CJD and other problems.  But they emphasized that
Alzheimer's was a diagnosis inferred from several indicators and could only
be conclusivly diagnosed at autopsy.  How much misery could be avoided if
they ever get a test that can provide a conclusive diagnosis up front?  What
an improvement that would be over the current situation for many of watching
people deterioate until the situation becomes drastic and undeniable.  I
didn't post the whole article (but included a link).  I found it
interesting.

Karen
---------------------------------------------
Brain Tests Help Evaluate Mental Condition
Feb 21, 11:02 AM (ET)

By JAMIE STENGLE
DALLAS (AP) - Bill Crist was angry and upset when his doctor diagnosed him
with dementia. But the 64-year-old retired pharmacist felt a little better
after going to the Center for BrainHealth for an evaluation, which showed
his language skills and memory were still quite strong.

Crist suffers from a neurodegenerative disorder that is associated with
Alzheimer's and Parkinson's disease. He said the follow-up test helped show
him which brain functions "look normal."

Such exams are becoming increasingly popular as aging Americans try to
differentiate between normal aging problems and the effects of neurological
conditions.

The three-hour screenings cost $350 and are not covered by insurance. Many
people get tested even when they aren't showing signs of brain problems.
-----
Slight downward shifts in mental capacity can be a sign of strokes, kidney
malfunction, stress or depression, said Dr. Sandra Chapman, the center's
director.

"The earlier you detect a glitch in the brain, the more that can be done,"
she said.

The best candidates for screenings are people who have noticed changes in
their memory, said Dr. Randolph Schiffer, chair of the department of
neuropsychiatry and behavioral science at Texas Tech University.
-----

http://apnews.myway.com/article/20050221/D88D0C9G0.html
Anthony Shipley - 26 Apr 2005 03:37 GMT
>When my MIL was diagnosed, the neurologist said her MRI showed "classic
>brain shrinkage patterns consistent with Alzheimer's".  They had done the
[quoted text clipped - 6 lines]
>didn't post the whole article (but included a link).  I found it
>interesting.

I was diagnosed without autopsy. That was sometime last year -- and was using
some new scanning technology. I know that the standard reprise is still that AD
is only correctly diagnosed post mortem--but is that really so? Anybody have a
reputable response?

-
Mind control is being able to make all the voices in your head take turns.

Mod as a hooter!
Jo Ann Malina - 26 Apr 2005 08:53 GMT
Anthony Shipley <astech@iinet.net.au> is alleged to have said:
>> I was diagnosed without autopsy. That was sometime last year -- and was using
>> some new scanning technology. I know that the standard reprise is still that AD
>> is only correctly diagnosed post mortem--but is that really so? Anybody have a
>> reputable response?

There are some indications that PET scans may provide a diagnosis on
living people.  Last spring, DuPuisR@webtv.net posted this to the group:

> PET imaging is said to show beta-amyloid in the brain of someone with
> AD, according to a report by the journal Annals of Neurology.
[quoted text clipped - 16 lines]
> contribute to better understanding of how the disease progresses and
> identify it in people who show no symptoms.

and Darryl posted a link to an article about PET and Alzheimer's:

http://mentalhealth.about.com/cs/aging/a/alzheimerspet_2.htm

Signature

Jo Ann Malina, make spamthis best to find my address
People say that life is the thing, but I prefer reading.
                                        -- Logan Pearsall Smith

Anthony Shipley - 26 Apr 2005 11:17 GMT
>and Darryl posted a link to an article about PET and Alzheimer's:

Yes, that was the test that allowed an A.D. diagnosis. PET had only become
available and I had mine in August 2004.

-
Mind control is being able to make all the voices in your head take turns.

Mod as a hooter!
Karen - 26 Apr 2005 13:18 GMT
My MIL received her diagnosis in 2000.  Actually, she had received another
diagnosis in 1999 and couldn't remember having seen that neurologist.   We
found that out while straightening out her business affairs.

It made me wonder if neurologists shouldn't ask their patients being seen
for suspected Alzheimer's for an additional family contact.  One of those
notions that makes common sense but probably wouldn't fly in the current
patient privacy environment.

Karen

> >and Darryl posted a link to an article about PET and Alzheimer's:
>
[quoted text clipped - 5 lines]
>
> Mod as a hooter!
 
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