kemadrin

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tj - 28 Oct 2004 01:40 GMT

Could sks please explain why procyclidine/kemadrin is contraindicated in
dementia? My wife used to be on this to try and combat restless legs but was
taken off it by her psychiatrist.

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Dennis P. Harris - 28 Oct 2004 04:03 GMT

> Could sks please explain why procyclidine/kemadrin is contraindicated in
> dementia? My wife used to be on this to try and combat restless legs but was
> taken off it by her psychiatrist.

try reading the manufacturer's data sheets. most of them are
online these days.

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Darryl - 28 Oct 2004 04:41 GMT

>Could sks please explain why procyclidine/kemadrin is contraindicated in
>dementia? My wife used to be on this to try and combat restless legs but was
>taken off it by her psychiatrist.

Kemadrin prevents binding of acetylcholine in the brain--this is
essentially the opposite of what AD drugs do. A quick search turned
up the following *potential* side-effects (note the last 4).

Darryl.

* Dry mouth
* Blurred vision
* Constipation
* Difficulty passing urine
* Nausea (feeling as if you are about to vomit)
* Vomiting
* Red swollen gums
* Nervousness/anxiety/agitation
* Rash
* Dizziness
* Mental confusion, disorientation
* Problems with memory and understanding
* Hallucinations (seeing or hearing things that aren't real)
* Disordered thinking

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