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Medical Forum / Diseases and Disorders / Alzheimer's / October 2004

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geriatric alcoholism

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megz - 07 Oct 2004 16:40 GMT
I am a new participant. I am looking for someone who has knowlege about
using the drug reminyl with alcohol. my father is 85, life long alcoholic
who is (just recently)beginning to show signs of alcoholic dementia - at
least that is what the doctor suspects it is. he lives alone and has had
his ups and downs with the booze. he was admitted to the hospital twice in
the past ten years with alcohol poisoning and made a remarkable recovery
each time. but did not stop drinking.
started him on the reminyl last spring. he seemed to clear up after the
six week trial period and after he was told what it was for, he refused to
take it.
now he is slipping again and i started him on the reminyl again, assuming
that he would cut down on the alcohol (like the did the previous time)
because it makes him feel better. at the end of six weeks i intended on
telling him what it was for again, hoping he would agree to take it. this
time, however, he is talking about some adverse side effects that may be
the result of using the drug with the alcohol. any experiences or
comments?  
Tumbleweed - 07 Oct 2004 16:59 GMT
>I am a new participant. I am looking for someone who has knowlege about
> using the drug reminyl with alcohol. my father is 85, life long alcoholic
[quoted text clipped - 13 lines]
> the result of using the drug with the alcohol. any experiences or
> comments?

Megz, look for messages here by barbara rose, if she doesn't see your
message try emailing her. She has LO with similar problem. Not sure what
reminyl is called in the UK the most common drugs here are memantine (aka
namenda in US) and aricept.
Obviously he is just using side effects as an excuse not to take them,
(given that the side effects of alchoholism are terminal & he's not looking
at giving that up I notice) so I would recommend the simple expedient of
lying*. Can you come up with a plausible resaon as to what they are, that he
would be happy with? Relable the bottle if necessary or take the pills out
and put them in a dispenser?

Signature

Tumbleweed

* aka 'loving deception' here. The point being, you wouldnt let a 2 year old
choose which medicines to take and which not to, but you might say "have one
of these nice M&Ms" instead of "take this pill"

email replies not necessary but to contact use;
tumbleweednews at hotmail dot com

megz - 07 Oct 2004 17:33 GMT
(first time user, i don't know if i am posting reply right to
tumbleweed...)
i had a disagreement with my brother about the ethics of giving someone
something they don't want to take. i presented a similar arguement "would
you let a two year old..." about giving him the drugs and he (my brother)
got all righteous about my dads civil rights. so, it is a problem within
the family, but i am doing it anyway because i feel as though this drug
can give him a chance to keep his mind and some dignity. now, with
possible side effects surfacing after two weeks (a report of double
vision) I am guilty. the doctor seems sympathetic to me, but i understand
he might be sticking his neck out (ethically) too, which is why I don't
want to call him. it is complicated.
Any logical conversation I have with my dad is soon washed away by the
alcohol.
i will look for the posts by Rose, but i am working so i will have to look
in the evening. thanks for you response.
Tumbleweed - 07 Oct 2004 18:13 GMT
> (first time user, i don't know if i am posting reply right to
> tumbleweed...)

Yes seems its working fine :-)

> i had a disagreement with my brother about the ethics of giving someone
> something they don't want to take. i presented a similar arguement "would
[quoted text clipped - 10 lines]
> i will look for the posts by Rose, but i am working so i will have to look
> in the evening. thanks for you response.

Your brother obviously isnt looking after your dad on  day to day basis :-(

Suppose your dad got a bit more delusional and decided to ...switch the gas
cooker on but not light it..or light it and put on an empty saucepan...and
leave it for several hours. .go for a walk at 2 am in his pajamas ina
blizzard....go 'home' (where 'home' is somewhere he lived 75 years ago that
no longer exists)...etc? Where are his civil rights then? Would your brother
just say 'ok dad tell me when you want to come back in the house'? Somehow,
I guess (hope?) not.

BTW, all these behaviours and more are quite characteristic and things like
this likely to happen at one point or another. There comes a point where you
have to take control, or the Az sufferer will harm themsleves or someone
else. Not to mention, the better they are due to drugs, the longer you can
care for them at home. There will also come a time when you cant look after
him anyway.

My cure for your brother is to get him to look after your father for a few
days.

Signature

Tumbleweed

email replies not necessary but to contact use;
tumbleweednews at hotmail dot com

augustwestern - 07 Oct 2004 19:25 GMT
> I am a new participant. I am looking for someone who has knowlege about
> using the drug reminyl with alcohol. my father is 85, life long alcoholic
[quoted text clipped - 13 lines]
> the result of using the drug with the alcohol. any experiences or
> comments?

This may seem harsh but IMO you are probably wasting your time until you get
the alcoholism stopped. You either need to make a decision to intervene and
assume full responsibility for your father's care or let him keep drinking
and not worry about his declining memory. At age 85 the damage is done and
any memory improvement will be slight and temporary at best.
You might get his driver's license revoked unless he happens to live within
walking distance of the liquor store.   best
megz - 07 Oct 2004 20:15 GMT
Take charge of an alcoholic? Sigh. Although this is somewhat off the
subject... (reminyl and alcohol effects.)He gave up driving years ago. He
can walk to the store. He denies the problem, hides the bottles and is
actually quite brilliant and devious at the same time. My worst nightmare?
That he will lose his mind and his body will survive another ten years -
longevity is in his genes. he is on no other medication. i have to say, i
tried navigating the families of alcoholic forums and there seem to be so
many troubled people there...they say that alcoholic dementia and
alzheimers are treated the same, which is why i decided to look for advice
here.
Darryl - 07 Oct 2004 20:23 GMT
>I am a new participant. I am looking for someone who has knowlege about
>using the drug reminyl with alcohol. my father is 85, life long alcoholic
[quoted text clipped - 6 lines]
>six week trial period and after he was told what it was for, he refused to
>take it.

>now he is slipping again and i started him on the reminyl again, assuming
>that he would cut down on the alcohol (like the did the previous time)
[quoted text clipped - 3 lines]
>the result of using the drug with the alcohol. any experiences or
>comments?  

Memantine (aka Reminyl, Axura and Ebixa) is an NMDA antagonist and
ethanol inhibits the NMDA receptor current (sorta like a dimmer
switch).  In English ;-), glutamate is an excitatory neurotransmitter
which gets out of whack in AD.  Take memantine to slow things down BUT
being an alcoholic will slow things even further.  What sort of
symptoms does he have?  

Here is yet another interesting case where memantine is apparently not
prescribed alongside a traditional AD medication such as Aricept (a
so-called acetylcholinesterase inhibitor) .  I suspect that the first
thing the doctor would have considered is a B-vitamin deficiency and
as Tumbleweed mentioned, see Barbara's post for more info.  If you
can't find the post on your computer, go to:

http://groups.google.com

and search for the following (include the quotes):

"Problem with Mum's alcohol"

Darryl.
Darryl - 07 Oct 2004 20:27 GMT
>I suspect that the first
>thing the doctor would have considered is a B-vitamin deficiency and
>as Tumbleweed mentioned, see Barbara's post for more info.  If you
>can't find the post on your computer, go to:

Well, aren't I a genius?  (must note subject lines and read posts
thoroughly in the future :-).  Does your Dad suffer from any B-vitamin
deficiencies?  
megz - 07 Oct 2004 22:11 GMT
Does your Dad suffer from any B-vitamin
deficiencies?
He got a B vitamin shot a few weeks ago. He should have been getting them
every six months, I guess, but it is hard to get him to see anybody. This
doctor took him on (as a favor I think) without his chart. He is paranoid
about his medical history, of course.
The problem is that he is very intelligent and you can have deep,
interesting discussions with him. He fools a lot of people. But then we
will get the strange, confusing phone calls that have gotten increasingly
weird - which is why the chronic brain syndrome or whatever they call it,
seems to be gaining. At this point he is going through a big bottle of
vodka every two days, along with beer and some wine. He doesn't eat much
and is horrid if we try to push food on him. He drinks a little can of
ensure, but I don't think it does much.  
Songbird - 07 Oct 2004 22:50 GMT
If he has B-12 deficiency (also called pernicious anemia), that in itself
can cause dementia. As far as I know, you have to have a shot every month
for it. (My mom does, anyway.)

Some docs give a general B-vitamin shot to stimulate appetite, increase
energy, etc.

Again, I'm afraid you need more testing, but if he won't cooperate and
guardianship is not an option, you may just need to let it run its course.
With that level of consumption, you're talking possible liver and kidney
failure from cirrhosis, congestive heart failure, ascites (fluid in the
abdomen) which can cause all sorts of problems, the list goes on. I don't
mean to sound negative or judgmental, just honest. (We just got my dad off
the alcohol with a liver scare. He's in early cirrhosis, but he says he
didn't drink that much. "Just four drinks a night," he said. Of course, I
would call his drinks doubles and he admits it was every night for the last
30 years.)

It's tough, megz. Hang in there and come vent when you need to.

Songbird

> Does your Dad suffer from any B-vitamin
> deficiencies?
[quoted text clipped - 10 lines]
> and is horrid if we try to push food on him. He drinks a little can of
> ensure, but I don't think it does much.
Boydette - 08 Oct 2004 06:59 GMT
Megz:

I read your post about your dad not eating and this just happened to my
alcoholic father who was drinking not eating and eventually collapsed.
He was dehydrated and in kidney failure by the time we realized
something else was wrong besides just being drunk.  

Dont want to scare you but this is the reality of an elderly parent who
"drinks their dinner".  Please dont let it get to that point....take
steps now to keep him from injuring himself further...I wish I had it to
do over again...I am here if you want to talk...Boydette
megz - 08 Oct 2004 14:05 GMT
Please dont let it get to that point....take
steps now to keep him from injuring himself further...I wish I had it to
do over again..
I have to tell you, we have had many attempts at intervention over the
years. His response "i want to live my life as i damn well please." we
even showed him the hospital and medical records (gotten by chance!) and
it doesn't have an effect. so how do you control somebody like that. he
won't survive another detox. so if we take him to the hospital (against
his will) it will surely kill him and we can't do that anyway because he
is still half sane and will scream about his civil rights.
botton line - it's sad, it's complicated...this is all taking place in an
upper class neighborhood, a lovely house filled with art and music. he is
at heart a survivor because he will call me or my brother when he starts
shaking (which usually mean is way over his limit) and i give him a
seraquel, which puts him to sleep. it works for now. and he has a beer
when he wakes up. Both my brother and I have children and after growing up
with an alcoholic father, I do not want them to have to suffer as I did
(and still do)which is why we don't want him to move in. somebody talks to
him or stops by everyday. he has a lady friend who drinks cocktails with
him. So, yes, it's complicated. I have to leave for work. thank you,
everyone who responded. megan
Gwen Love - 08 Oct 2004 19:18 GMT
Megan, seems to me you are and have been doing all you can, and if he does
drink himself to death you cannot help him.  You have my sympathy and
prayers.
Gwen

> Please dont let it get to that point....take
> steps now to keep him from injuring himself further...I wish I had it to
[quoted text clipped - 17 lines]
> him. So, yes, it's complicated. I have to leave for work. thank you,
> everyone who responded. megan
Dennis P. Harris - 08 Oct 2004 07:29 GMT
> He doesn't eat much
> and is horrid if we try to push food on him. He drinks a little can of
> ensure, but I don't think it does much.  

if he doesn't have another bout of alcohol poisoning, due in part
to the slow failure of his liver, he might die of malnutrition or
dehydration.
megz - 07 Oct 2004 22:21 GMT
What sort of
symptoms does he have?  
oh - sorry, i should read posts more carefully...dinner time here. um, he
had an episode with double vision. i was at first worried that it might be
a slight stroke, but after reading about side effects of the reminyl,
thought that it might be that. anyway, i appreciate any insight. taking
any drugs is a big deal for him. he had just gotten used to taking vioxx
when they recalled it.
Barbara Rose - 08 Oct 2004 23:05 GMT
Hello Megan

Yes, I know exactly what you are going through as I have had this same
situation with both my mother and father.  My father is now dead but the
problem is ongoing with my mother who drinks a litre (35 ozs a day) but
denies it.

She was living with us for two years and in complete denial, would never
admit how much she was drinking and I really don't think she even
remembered.  She was put on reminyl, in England it is called Aricept and
eventually she was diagnosed with Vit B deficiency and has to take folic
acid, iron and Vit B shots every month.

Like your Dad she doesn't see that she should cut down her drinking but now
she is in a residential home and her latest blood tests have caused the
doctor to limit her sherry to 1/2 pt a day.  Of course she is not happy with
this and swears she hardly drinks, all in the same breath.  It has affected
her responses, memory and all functions.  To be honest at her age (almost
89) I don't see the point of prolonging her life by depriving her of what
she has drunk for over 20 years, but I am no longer in charge of her
medication and the doctor is adamant that she must limit her intake.

I asked the doctor about whether the alcohol interferes with the medication
and she said a moderate alcohol intake would be fine, but not what your
father is drinking.  I too, am having a problem with certain members of the
family championing 'human rights' so I know how you feel and any
conversation with my Mum is a waste of time as she forgets the minute she
has finished her sentence.  I also am living your fear, she has lost her
mind but her body is very well and all her family have lived to very old
age.  I think that at an advanced age the brain cells have already been
destroyed and there is little point in trying to
stop them drinking when it is their only pleasure.

I really feel for you because I am in the same situation.  In my case I made
the very difficult decision to put Mum into care as I couldn't cope any
more.  It was only a matter of time before she had a bad accident as she was
always falling after drinking and became very aggressive and hard to handle.
If you have any more questions that I can help with let me know.  I also
know what it's like when they won't eat and only want the drink.

Take care

Barb in UK
> I am a new participant. I am looking for someone who has knowlege about
> using the drug reminyl with alcohol. my father is 85, life long alcoholic
[quoted text clipped - 13 lines]
> the result of using the drug with the alcohol. any experiences or
> comments?
megz - 09 Oct 2004 00:43 GMT
Well, thank you Barbara. I am sorry that we share the same experiences,
although it is a comfort to know others can understand the complications.
I appreciate the advice from you (and others.) I don't believe we could
find a nursing home that would let him drink - they seem to outlaw that
here.  I will talk to the pharmacist tomorrow. I will talk to the doctor
after the six week trial period with reminyl is over. I will talk with
other family members and see if they think it is helping, and then we will
decided whether to keep him on it without him knowing what it is for. It
does seem as though he is eating more. The instructions on the reminyl
pack) say "take with breakfast and dinner" and it reminds him to eat. (He
thinks the pills are for his stiff back though.)The rest of the day is
filled with naps and TV. He reposrts to me on the presidential debates and
whatever Tony Blair is saying in the House of Commons. So that is our
holding pattern for now. Thanks again - megan
Boydette - 09 Oct 2004 04:28 GMT
Megan

I want to say I dont know what I was thinking when I posted my last
response. I guess I was just in a relatively emotional mood.  I of all
people know how hard it is to have alcoholic parents as both of mine
are.

It is definitely a catch 22 situation and trying to control an alcoholic
who is also going out of their mind as well as neglecting their physical
health is damn near impossible.

Some of the advice I got along the way as I tried so hard to avoid the
inevitable was to just let them go and do whatever and let the cards
fall where they may.  Eventually my dad was in serious trouble and is
now in a nursing home where he continues to be delusional and confused.

My mom is also showing signs of AD although at this point all we have
gotten is a tentative diagnosis from an ER doc.  She is getting worse by
the day especially now being without dad and continuing to drink..  We
are just taking one day at a time as it seems that is what you are also
doing.  You have my best wishes and support in what you are going thru.
Ufortunately as has already been pointed out to me it wont end until
they are gone.
Sad but true.

Boydette
Dennis P. Harris - 09 Oct 2004 10:02 GMT
> It is definitely a catch 22 situation and trying to control an alcoholic
> who is also going out of their mind as well as neglecting their physical
> health is damn near impossible.

It was the same with my mother with smoking, even though her
emphysema was getting worse by the day.  She was in total denial
about how it was destroying her ability to do anything physical
until she was hypoxic and weak all the time, when it was too late
for any kind of lung recovery.  Addicts are all the same --- they
have to hit rock bottom and want to quit or they will never do
so.
megz - 09 Oct 2004 14:16 GMT
re: boydett and dpharris. thank you. i think what is especially sad is the
people with alzheimers have no choice in the matter. the alcoholic has the
option to modify or correct his behavior. at one point, in the seventies,
he was told to see a psychiatrist (by the firm he was working for,) who
suggested that he was manic depressive and should be medicated. those that
lived with him agreed - he did not. he has been self medicating with the
alcohol since he was sixteen. hopefully, we are becoming more aware of
chemical imbalances in the brain that lead to addiction. although it
always depends on the individual resolve to conquer it. thanks again.megan

Dennis P. Harris - 09 Oct 2004 18:58 GMT
> at one point, in the seventies,
> he was told to see a psychiatrist (by the firm he was working for,) who
> suggested that he was manic depressive and should be medicated. those that
> lived with him agreed - he did not. he has been self medicating with the
> alcohol since he was sixteen.

yep.  alcohold and nicotine are the two most common self-med
drugs for bipolar and depressed people.
 
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