Ditropan interfering with Reminyl?

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Bill Hermsmeier - 20 Sep 2004 15:43 GMT

Howdy,

I withheld Ditropan (This medicine is an antispasmodic anticholinergic agent
used to treat overactive bladder with symptoms of urinary incontinence,
urgency, and frequency.) for a couple weeks after reading it may reduce the
effectiveness of Reminyl.

? Drug or food interactions: Cholinergic drugs may increase effects of other
drugs that also have cholinergic effects, such as tacrine (Cognex),
donepezil (Aricept), galanthamine (Reminyl), and rivastigmine (Exelon).
Anticholinergic drugs ... will likely reduce the effect of cholinergic
drugs.
http://www.emedicinehealth.com/articles/40849-5.asp

Do you guys have any thoughts on this? My Mom only needs one Ditropan xl
10mg every 3 days to get some relief, and the extra sleep for her and me are
not insignificant. I gave her another one this morning.

Regards,
Bill

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Darryl - 21 Sep 2004 04:36 GMT

>I withheld Ditropan (This medicine is an antispasmodic anticholinergic agent
>used to treat overactive bladder with symptoms of urinary incontinence,
[quoted text clipped - 6 lines]
>Anticholinergic drugs ... will likely reduce the effect of cholinergic
>drugs.

Yes, AChE inhibitors are considered cholinergic drugs and
anti-spasmodics anti-cholinergics.

>http://www.emedicinehealth.com/articles/40849-5.asp
>
>Do you guys have any thoughts on this? My Mom only needs one Ditropan xl
>10mg every 3 days to get some relief, and the extra sleep for her and me are
>not insignificant.

Then stick with the drug; however, you might ask your doctor about
Detrol (tolterodine) which should accomplish the same effect as
Ditropan yet it isn't *as* active in the CNS. That said, there is an
article titled: "Tolterodine and Memory--dry but forgetful".

Unfortunately, these drugs are relatively new and the data that we
need isn't available yet.

What else is new, eh?

Take care,
Darryl.

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Rose - 23 Sep 2004 08:30 GMT

>Then stick with the drug; however, you might ask your doctor about
>Detrol (tolterodine) which should accomplish the same effect as
[quoted text clipped - 3 lines]
>Unfortunately, these drugs are relatively new and the data that we
>need isn't available yet.

Well, according to my mother's urologist and gerontologist, all bladder control
drugs including Detrol affect memory/orientation.

For her doctors, whether to use it, and how infrequently, has been a matter of
balancing the risk/rewards.

___
"Oh I like this idea...Oh yeah. This can't miss." -- Jerry Seinfeld

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LynnSmyth - 24 Sep 2004 20:03 GMT

Have any of you found any other methods to help control bladder loss?
My mother is at the maximum dose of ditropan. It helped for quite
awhile. It is a huge problem now. Mainly at night. Any other
suggestions would be appreciated.
Thank you.
Lynn

> Howdy,
>
[quoted text clipped - 16 lines]
> Regards,
> Bill

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Evelyn Ruut - 25 Sep 2004 12:46 GMT

> Have any of you found any other methods to help control bladder loss?
> My mother is at the maximum dose of ditropan. It helped for quite
> awhile. It is a huge problem now. Mainly at night. Any other
> suggestions would be appreciated.
> Thank you.
> Lynn

We simply went to depends for overnight. Eventually she needed them all
the time, but at first it was just overnight.

Signature

Regards,
Evelyn

(to reply to me personally, remove 'sox")

>> Howdy,
>>
[quoted text clipped - 20 lines]
>> Regards,
>> Bill

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