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Medical Forum / Diseases and Disorders / Alzheimer's / July 2004

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ABC news article on drug for alzheimers

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Evelyn Ruut - 20 Jul 2004 23:18 GMT
I checked, and guess what drug they are speaking of?  ARICEPT!
Article is at this link.

http://abcnews.go.com/wire/Living/ap20040718_1542.html

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Regards,
Evelyn

(to reply to me personally, remove 'sox")

Darryl - 21 Jul 2004 01:27 GMT
>I checked, and guess what drug they are speaking of?  ARICEPT!
>Article is at this link.
>
>http://abcnews.go.com/wire/Living/ap20040718_1542.html

Heh...I prefer guessing as opposed to looking into the facts.  ;-)
They can't seem to keep their minds straight on the usefulness of
Aricept, eh?  I quickly read the article and found that they're now
downplaying vitamin E.  You probably recall that within the last year,
a study found that vitamins C and E were found to be useful in the
incidence and prevalence of AD.  

However, thanks to Mary--it's good to know, though, that the new
vaccine (Alzhemed) is showing great promise and it's recently reached
Phase III in the States.

Hope everyone's having a good summer,
Darryl.
Mary Gordon - 21 Jul 2004 13:23 GMT
What gets me about this is that they have given a bogus label "MCI" to
what is obviously early AD in the majority of cases.

Its a mistake to say most people with "MCI" go on to develop
Alzheimer's, like the events are separate. The truth is, what they are
calling "MCI" is just the symptoms of AD in such an early stage that
it can't be easily diagnosed - the symptoms have to evolve and get
worse. They are probably trying to save people's feelings by calling
it MCI instead of probable early AD, which would be more accurate. And
of course taking a drug that slows down AD is going to slow down MCI
since they are one and the same!!!

There are lots of illnesses like that. I have had many friends with
wierd neurological or muscle problems where they bounced from doc to
doc for years because they were in the very early stages of MS or some
arthritic thing, and the early symptoms are too subtle and variable
for a definitive diagnosis.  I don't think this is anything different.

Mary G.
Rose - 29 Jul 2004 09:22 GMT
>Subject: Re: ABC news article on drug for alzheimers
>From: Mary_Gordon@tvo.org  (Mary Gordon)
[quoted text clipped - 12 lines]
>of course taking a drug that slows down AD is going to slow down MCI
>since they are one and the same!!!

Hi, my name is Rose.

I'm not so sure m.c.d. and Alz. are one and the same. Alzheimers isn't the only
cause of confusion and dementia.  In the early stages it's very hard to know if
the person has Alzheimers.  Why diagnose Alzheimers if it's too early to tell?
I read that one in nine people diagnosed with Alzheimers are MISdiagnosed and
it turns out they have another problem. That's a large number of people.

My mom was diagnosed with cognitive disorder not otherwise specified three
years ago.  Several months ago she was diagnosed with mild to moderate
dementia.  One doctor thinks she has vascular dementia because he says her
personality is too much intact for it to be Alzheimers.  Another doctor thinks
it's either Alzheimers or Alzheimers mixed with vascular dementia.  If even now
that she has dementia, the doctors don't agree on what she has, then it makes
sense that they didn't diagnose her with Alzheimers when she had only mild
confusion and memory loss.

I was told when she was diagnosed with cognitive disorder that it was possible
she had Alzheimers and we had to keep our eyes open.  To be on the safe side
they put her on Aricept and Vitamin E immediately.  When she started declining
more precipitously three years later I had her reevaulated and the doctors came
up with their differing theories.

Long story short, I don't think it's bad for doctors to refrain from rushing to
judgment and diagnosing people withe Alzheimers before all the facts are in.
At least in my mother's case, lack of a firm Alz. diagnosis didn't hurt her.
She still received necessary treatment.

>There are lots of illnesses like that. I have had many friends with
>wierd neurological or muscle problems where they bounced from doc to
>doc for years because they were in the very early stages of MS or some
>arthritic thing, and the early symptoms are too subtle and variable
>for a definitive diagnosis.  I don't think this is anything different.

If the early symptoms are too subtle to tell, isn't it better that doctors hold
off on diagnosing a catastrophic illness until they know for sure?  I agree
that patients should be prepared for the possiblity of having something serious
so they can prepare, but what's the point of making a premature diagnosis?

___
"How do they know the dog food is any good?  Who tastes it?" -- Elaine,
"Seinfeld"
 
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