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Medical Forum / General / Alternative / July 2008

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ironjustice - 03 Jul 2008 14:20 GMT
Reduced Hygiene, Illicit Drug Use Linked to CA-MRSA in Men Who Have
Sex With Men

Laurie Barclay, MD

http://www.medscape.com/viewarticle/577001

July 2, 2008 — Reduced hygiene and use of crystal methamphetamine were
associated with acquisition of community-associated methicillin-
resistant Staphylococcus aureus (CA-MRSA) in men who have sex with men
(MSM), according to the results of a case-control study reported at
the 2008 Annual Conference on Antimicrobial Resistance in Bethesda,
Maryland.

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ironjustice - 25 Jul 2008 14:13 GMT
Parasitic Worm Infections Increase Susceptibility To AIDS Viruses
ScienceDaily (July 24, 2008) — Persons infected with schistosomes, and
possibly other parasitic worm infections, may be more likely to become
infected with HIV than persons without worm infections, according to a
new study.

Researchers at the U.S. Centers for Disease Control and Prevention
(Atlanta, United States) and the Dana-Farber Cancer Institute and
Harvard Medical School (Boston, United States) found that the
infectious dose of an HIV-like virus necessary to infect rhesus
macaques was 17-fold lower in animals with acute schistosomiasis than
in controls.

The study represents a novel in vivo demonstration that parasitic
worms increase a host's susceptibility to becoming infected with an
AIDS-causing virus. The macaques co-infected with Schistosoma mansoni
also demonstrated higher peak viral loads and higher memory cell
concentrations of virus, both predictors of more rapid progression to
AIDS. These findings are consistent with the hypothesis that persons
living in areas highly endemic for parasitic worms may also have a
higher risk of acquiring HIV/AIDS.

Previous studies by this and other research groups have demonstrated
that presence of schistosome infections increases viral replication in
animal or human hosts with established immunodeficiency virus
infections. The earlier findings, combined with the increased
susceptibility to AIDS virus transmission shown in this study, may
have profound public health implications for areas of the world where
both parasitic worms and HIV-1 are endemic.

--------------------------------------------------------------------------------

Journal reference:

Chenine A-L, Shai-Kobiler E, Steele LN, Ong H, Augostini P, et al.
Acute Schistosoma mansoni Infection Increases Susceptibility to
Systemic SHIV Clade C Infection in Rhesus Macaques after Mucosal Virus
Exposure. PLoS Neglected Tropical Diseases, 2(7): e265 DOI: 10.1371/
journal.pntd.0000265

Who loves ya.
Tom

Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh

Man Is A Herbivore!
http://tinyurl.com/4rq595

DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

> Reduced Hygiene, Illicit Drug Use Linked to CA-MRSA in Men Who Have
> Sex With Men
[quoted text clipped - 18 lines]
>
> DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk
ironjustice - 25 Jul 2008 14:36 GMT
On Jul 25, 6:13 am, ironjustice <teamtan...@hotmail.com>
wrote:profound public health implications <<

HIV and Crystal Meth: A Deadly Synergy

By Mara Burney

It's no secret that crystal methamphetamine is oozing eastward, into
urban areas, and up the socioeconomic ladder.  But with all the recent
media coverage, one has to wonder...is the meth epidemic something
novel, or is it just the same old story with a new drug playing the
lead role?  Skeptics and critics of the "War on Drugs" point out that
as long as demand exists for a drug, law enforcement is practically
powerless to prevent its use.  Some even suggest that the crystal
methamphetamine problem, which is for the moment gaining widespread
attention in the mainstream media, will plateau or decline (as with
crack after the 1980s), despite the ominous tone of news stories.

But there is a big difference between crystal methamphetamine and
other illicit drugs, one that makes it especially worthy of aggressive
intervention and attention by public health authorities and the media
alike: the intersection between the meth epidemic and the HIV/AIDS
epidemic.

Crystal meth is a highly addictive nervous system stimulant that can
be snorted, smoked, injected, or swallowed.  Because the drug
simultaneously increases sexual drive, enhances the sexual experience,
and decreases inhibitions, meth use often means that safer sex
practices are abandoned, putting users at much greater risk for HIV
and other sexually transmitted infections.(1)  For this reason, meth
has the potential to undo a lot of the progress that has been made
since the onset of the HIV/AIDS epidemic in encouraging safe-sex
practices.  Research on gay and bisexual men especially indicates a
"condom fatigue" in that community, especially at "circuit parties" in
big cities, which sometimes host as many as 80,000 participants, 25%
of whom report being HIV-positive and 43% of whom report using crystal
meth at the parties.  An astounding 39% of these HIV-positive men
report engaging in unprotected anal intercourse during the parties.
(2)  Alarmingly, data from the L.A. Gay and Lesbian Center Survey in
2004 show that nearly one third of men testing positive for HIV report
having used crystal meth since their last test (or in the last two
years, whichever was most recent), and gay men in California who use
meth are more than twice as likely to be HIV-positive than those who
don't.(3)  The "use a condom every time" message doesn't seem to be
getting through as well as it used to, and many think that meth's
judgement-impairing effect is partially to blame.  In other words, no
amount of traditional sex education can be effective if this drug
makes users abandon everything they have learned.

Meth use is also quite prevalent among gay and bisexual men already
infected with HIV.  Meth poses additional dangers for this group
because addiction can lead to a lapse in taking medications (which can
lead to treatment resistance), weight loss, and vitamin depletion.
According to the NYC Department of Health and Mental Hygiene, meth use
can also "suppress immune system responses to HIV or other infections,
cause dangerous interactions with HIV medications, increase HIV viral
activity, and accelerate HIV-related dementia and other health
problems."(4)

This is not to say that gay and bisexual men are the only ones using
meth -- nothing could be further from the truth -- but this group
warrants special attention because of the documented relationship
between meth use and HIV transmission.  Unprotected receptive anal
intercourse with multiple partners is the most likely mode of HIV
transmission.  Because crystal meth deadens pain receptors, users are
even more likely to engaged in prolonged, rough, and repeated
encounters, which can lead to torn tissue and increase vulnerability
to transmission.

According to the Gay Men's Health Crisis, those in the gay community
often fall prey to meth use because of unique social or psychological
pressures; meth bestows a feeling of belonging, sexiness, and
confidence upon the user.  Training for addiction-treatment
professional aimed at addressing the feelings of low self-esteem and
alienation that abet addiction would be a logical first step in
loosening meth's grip on the gay community.  The integration of
addiction treatment, HIV intervention, and mental health services is
also critical.

Methamephetamine use is not just an issue of drug policy -- it is an
issue of communicable disease transmission and should be treated as
such.  Confronting the HIV epidemic without an effective anti-crystal-
meth program is like trying to reduce heart disease without tackling
cigarette smoking.  Because no proven pharmacological intervention yet
exists for this highly addictive drug, the development of harm
reduction strategies and cognitive behavioral therapies is crucial.
Here's hoping that no matter what their political stance regarding the
"War on Drugs," the gatekeepers of policy, financial resources, and
logistical knowhow will come to see crystal meth as a public health
priority.

(1)Ghaziani, A. and D. Cook.  "Reducing HIV Infections at Circuit
Parties: From Description to Explanation and Principles of
Intervention Design."  J Int Assoc Physicians AIDS Care.  4 (1); 2005,
pp. 32-46.
(2) ibid.
(3) Hereida, C.  "Crystal Meth Fuels HIV."  San Francisco Chronicle.
May 4, 2003.
(4) Health Bulletin: Methamphetamine and HIV.  Health and Mental
Hygeine News (NYC DOHMH), April 2004.
(5) "Confronting Crystal Methampetamine Use in New York City."  Gay
Men's Health Crisis, New York, July 2004.

Mara Burney is a research associate with the American Council on
Science and Health (ACSH.org, HealthFactsAndFears.com).  Also: a new
report confirms that meth users are three times as likely to acquire
HIV, as noted in the San Francisco Chronicle.

This information was found online at:
http://www.acsh.org/factsfears/newsID.615/news_detail.asp

Who loves ya.
Tom

Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh

Man Is A Herbivore!
http://tinyurl.com/4rq595

DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

> Parasitic Worm Infections Increase Susceptibility To AIDS Viruses
> ScienceDaily (July 24, 2008) — Persons infected with schistosomes, and
[quoted text clipped - 69 lines]
>
> - Show quoted text -
 
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