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Medical Forum / General / Alternative / May 2008Astronautical Oxidation
Astronauts face space age risk Astronauts who spend too long in space may age prematurely and become more prone to cancer, new research suggests. Radiation in space can cause damage to living tissue The findings from scientists in the US could have major implications for plans to build moon bases and send explorers to Mars. The risks come from exposure to "space radiation" according to the researchers, who were funded by the American space agency Nasa. They found evidence that the high energy particles which float through space can have a harmful effect on mice. Cancer risk In a new report, the scientists claim that the particles can damage DNA. They found that the biggest effect was on the gut, and that is likely to lead to an increased risk of colon cancer. The mice who were exposed to radiation also aged prematurely, with their fur turning grey. Radiation exposure, either intentional or accidental, is inevitable during our lifetimes Dr Kamal Datta, who led the study at Georgetown's Lombardi Comprehensive Cancer Centre, said: "Radiation exposure, either intentional or accidental, is inevitable during our lifetimes. But with plans for a mission to Mars, we need to understand more about the nature of radiation in space." The kind of radiation found in space is known as high LET (linear energy transfer) radiation. It can cause concentrated damage to living tissue. People on Earth are shielded from it by the planet's atmosphere, but in space there is nothing to stop astronauts being blasted by the particles. Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > Astronauts face space age risk > Astronauts who spend too long in space may age prematurely and become [quoted text clipped - 48 lines] > DEAD PEOPLE WALKING > http://tinyurl.com/zk9fk This should be nothing new. It has long been known that space is a hostile environment. In space in the current generation of low mass aluminium can used as spacecraft, astronauts get high exposures to both high LET and low LET radiation. All of this would serve a mimetic of the aging process. This has been known for at least 5 decades. Space travel beyond the moon will require sheilding both passive mass shielding and electromagnetic shielding. Either that or perhaps society should send former national leaders and representives in the vessels with no shielding. On Apr 30, 1:01 pm, "trigonometry1...@gmail.com |" <trigonometry1...@gmail.com> wrote: Space travel beyond the moon will require sheilding both passive mass shielding and electromagnetic shielding. << Or turn the pressure up in the cabin. Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > > Astronauts face space age risk > > Astronauts who spend too long in space may age prematurely and become [quoted text clipped - 64 lines] > > - Show quoted text - Turning up the pressure has nothing to do with stopping the radiation... ...not to mention the bone de-calcification that occurs from just being in zero-G for extended periods.  Signature- Rufus (whom was once recruited as an astronaut when he was younger and well, and decided that it was a job he just plain didn't want.) > On Apr 30, 1:01 pm, "trigonometry1...@gmail.com |" > <trigonometry1...@gmail.com> wrote: Space travel beyond the moon will [quoted text clipped - 69 lines] >> >> - Show quoted text - > Turning up the pressure has nothing to do with stopping the radiation... He wants to say that by turning up the pressure in the cabin you reduce the red blood cell count and therefore iron content in the blood. With less iron there is less oxidation of biological membranes which are primary target of radiation. You can also put the people on a coconut/SFA-only diet 2 years prior to the mission and achieve similar effect since the Omega-6 and 3 are much more susceptible to radiation-induced oxidation than the Omega-9 Mead acid which replaces them when you limit your "EFA" intake. But a better solution would be to remove some bone marrow (stem cells) from the cosmonauts (even better when they are young) and keep it safe here on the Earth till they return and then put it back into them. Taka On May 3, 7:38 am, Taka <taka0...@gmail.com> wrote:He wants to say that by turning up the pressure in the cabin you reduce the red blood cell count and therefore iron content in the blood. << This proved to be a futile theory though with a little checking they keep the pressure in the shuttle calibrated at sea level even better than commercial airlines. So we are back to the vitamin E / antioxidant depletion by .. ? .. oxidation .. ? Vitamin E was / is ? being used to prevent the anemia which happens in space. It would be something other than the pressure which is causing the increased oxidation in the astronaut and give more credence to the increased rays. Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > > Turning up the pressure has nothing to do with stopping the radiation... > [quoted text clipped - 11 lines] > > Taka I think they keep it regulated to 8K feet MSL - I know for a fact that that's what they do with airliners flying above 10-12K. Anything greater requires the structure to become too heavy. None of the below makes any sense at all...the only thing you can do to decrease the effects of radiation is to stay away from it. The best protection from radiation is actually dirt - protective effect is directly proportional to density. There is no way to combat radiation with chemistry. Signature- Rufus > On May 3, 7:38 am, Taka <taka0...@gmail.com> wrote:He wants to say > that by turning up the pressure in the cabin you reduce the red blood [quoted text clipped - 39 lines] >> >> Taka On May 3, 9:58 am, Rufus <n...@home.com> wrote:I think they keep it regulated to 8K feet MSL - I know for a fact that that's what they do with airliners flying above 10-12K. Anything greater requires the structure to become too heavy. None of the below makes any sense at all...the only thing you can do to decrease the effects of radiation is to stay away from it. The best protection from radiation is actually dirt - protective effect is directly proportional to density. There is no way to combat radiation with chemistry. << http://www.yale.edu/ynhti/curriculum/units/1987/6/87.06.03.x.html The shuttle is kept at sea level pressure .. unless cabin pressure is different from air pressure ? AIR Air pressure inside the cabin of the Shuttle is maintained at 1,033 grams per square centimeter (14.71 lbs.), the same as that on earth at sea level. These guys sure a .. keeping WITH the times .. On May 3, 9:58 am, Rufus <n...@home.com> wrote:There is no way to combat radiation with chemistry. << This has been known at least since .. 2001 .. A. R. Kennedy1 , J. Guan1 and J. H. Ware1 (1) Department of Radiation Oncology, University of Pennsylvania School of Medicine, 195 John Morgan Building, 3620 Hamilton Walk, Philadelphia, PA 19104-6072, USA Received: 20 September 2006 Accepted: 27 February 2007 Published online: 27 March 2007 Abstract Of particular concern for the health of astronauts during space travel is radiation from protons and high atomic number (Z), high energy particles (HZE particles). Space radiation is known to induce oxidative stress in astronauts after extended space flight. In the present study, the total antioxidant status was used as a biomarker to evaluate oxidative stress induced by proton and HZE particle radiation in the plasma of CBA mice and the protective effect of dietary supplement agents. The results indicate that exposure to proton and HZE particle radiation significantly decreased the plasma level of total antioxidants in the irradiated CBA mice. Dietary supplementation with l-selenomethionine (SeM) or a combination of selected antioxidant agents (which included SeM) could partially or completely prevent the decrease in the total antioxidant status in the plasma of animals exposed to proton or HZE particle radiation. These findings suggest that exposure to space radiation may compromise the capacity of the host antioxidant defense system; this adverse biological effect can be prevented at least partially by dietary supplementation with agents expected to have effects on antioxidant activities. http://www.springerlink.com/content/x84v27578w8q27wk/ -------------------------------------------------------------------------------- Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > I think they keep it regulated to 8K feet MSL - I know for a fact that > that's what they do with airliners flying above 10-12K. Anything [quoted text clipped - 54 lines] > > - Show quoted text - > On May 3, 9:58 am, Rufus <n...@home.com> wrote:I think they keep it > regulated to 8K feet MSL - I know for a fact that [quoted text clipped - 13 lines] > The shuttle is kept at sea level pressure .. unless cabin pressure is > different from air pressure ? Sort of - it's sort of a relative measurement. At least that's what I always remember about it in terms of what it's trying to tell me. Standard sea level static pressure is 14.7 psia, and cabin pressure is whatever pressure the cabin happens to be pressurized to, expressed in terms of equivalent pressure at a Standard Atmosphere equivalent altitude. Example - in an airliner cabin pressurized to 8K MSL, you are walking around in about a 10.9 psia Standard atmosphere; while the Standard outside pressure at 35K MSL where the jet is flying is only about 3.5 psia. Thus, the higher the differential the heavier the structure has to become to withstand it - and that's why airliners (and military aircraft) make the trade-off on pressurization with operating altitude. > AIR > Air pressure inside the cabin of the Shuttle is maintained at 1,033 > grams per square centimeter (14.71 lbs.), the same as that on earth at > sea level. > These guys sure a .. keeping WITH the times .. I'll believe NASA, I guess... http://www.nas.nasa.gov/About/Education/SpaceSettlement/teacher/course/merc.html The fact that are able to do this speaks to the advancements in loft capability, I think. From a historical 5 psi to 14.7 psi in one system-step is a huge increase...but again, they don't say "psia", so it may not really be "sea level" equivalent pressure. psia= atmospheric + gauge, so since NASA doesn't specify, I'm not clear on what they really mean...I'd be more comfortable if they said "1 ATM". > On May 3, 9:58 am, Rufus <n...@home.com> wrote:There is no way to > combat radiation with chemistry. << [quoted text clipped - 31 lines] > supplementation with agents expected to have effects on antioxidant > activities. ...I wonder if they've tried to breed these animals, studied any alterations in their genetics, and what their subsequent cancer rates are with respect to established norms... Ionizing radiation WILL irreversibly harm you over the long term, even if you do manage to find ways to keep yourself functional in the short term...no thanks. After spending some time working around it, I've learned to just plain avoid it whenever possible - because that's really the only "protection" from it. Signature- Rufus This is nothing new. Cosmic rays, the elementary particles blasted across space by supernova etc., kill. Shielding from cosmic rays is a big engineering problem. Water, interestingly enough, may be the best shield. Another major problem is zero gravity, which will atrophy muscles and bones. 3 years in zero gravity would be catastrophic to a person. Another major problem is isolation/loneliness and being cooped up with the same people in a very small space for 3 years. And sex, how will that work out in space: jealousy, pregnancy, lovers fights, etc. etc. etc. Getting to Mars is a much bigger problem than most people imagine. > This is nothing new. Cosmic rays, the elementary particles blasted > across space by supernova etc., kill. Shielding from cosmic rays is a [quoted text clipped - 10 lines] > > Getting to Mars is a much bigger problem than most people imagine. If human space travel is going to work it certainly will require more massive, faster vessels, a good natural lighting replacement, have system to use the spin of the disc shaped craft to replacement gravity etc. The vessels will not look like Apollo or even the GWB special NASA is working on currently. And it would help if the destination wasn't just a manmade cave on Mars. Too deep a gravity well in my opinion anyway for the first goal beyond the Moon. >Astronauts face space age risk >Astronauts who spend too long in space may age prematurely and become [quoted text clipped - 48 lines] >DEAD PEOPLE WALKING >http://tinyurl.com/zk9fk Anything having to do with science and measurement can be done right here from earth using unmanned space missions. I can think of nothing, no prison sentence, no sure way to insanity then spending it on a spaceship to Mars. >> Astronauts face space age risk >> Astronauts who spend too long in space may age prematurely and become [quoted text clipped - 53 lines] > nothing, no prison sentence, no sure way to insanity then spending it > on a spaceship to Mars. ...part of the psych-eval for becoming an astronaut has to do with just plain figuring out if you are someone that someone else could tolerate being locked up in a can with for an extended period. Signature- Rufus |
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