Anyone remember the 'standin' for corticosteroids.. ?
Coincidentally a **phosphate** containing substance.
Phosphate remediates iron.

Le Rhun E, Soto Ares G, Pécheux N, Destée A, Defebvre L
[Superficial hemosiderosis of the central nervous system improved by
corticosteroids.] [JOURNAL ARTICLE]
Rev Neurol (Paris) 2008 Mar; 164(3):264-270.

INTRODUCTION:
Superficial siderosis is of the Central Nervous System (CNS) is an
uncommon and often disabling disorder. There is no evidence that any
treatment, including removal of an identified source of bleeding,
affects disease progression.
OBSERVATION:
We report the case of a 49-year-old woman exhibiting progressive and
various neurological disorders associating chorea, pyramidal syndrome,
cerebellar ataxia, cognitive disorders and cranial nerve deficits. She
had a prior history of right occipital arterioveinous malformation
(AVM) revealed four years before by ventricular hemorrhage. The AVM
was treated by radiosurgery. Because of a pronounced progression of
the symptoms, treatment with steroid therapy was initiated before the
diagnosis of siderosis of the central nervous system was asserted by
magnetic resonance imaging (rim of hypo-intensity due to hemosiderin
around the brainstem, the cerebellum and the spinal cord on T-2
weighted and gradient echo T-2* imaging) and cerebrospinal fluid (CSF)
examination (high CSF levels of iron and ferritin). Over the next
months the neurological condition improved under steroid therapy.
CONCLUSION:
Our observation is interesting because of the chorea movement
disorders which are rarely reported in the disease and because of the
improvement of the neurological condition after steroid therapy which
is described in only another case in the literature. Steroid therapy
could constitute a new track for the treatment of siderosis of CNS.

Revue neurologique [Rev Neurol (Paris)]

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