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Medical Forum / General / Alternative / March 2008

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Probucol and Niceritrol and Hypercholesterolemia

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ironjustice - 15 Mar 2008 14:43 GMT
Sooo .. would this be .. again .. simply the chaff of your grain .. ?
Niacin and an iron chelator ..

"Seventeen patients".
"Thirteen subjects achieved normal levels of cholesterol"

Title: New combined therapy of niceritrol and probucol on heterozygous
familial hypercholesterolemia.
Author: Yamamoto, K : Fukushima, N : Ozaki, I : Setoguchi, Y :
Yanagita, T : Sakai, T
Citation: Artery. 1991; 18(3): 133-49
Abstract:
Seventeen patients with heterozygous familial hypercholesterolemia
were sequentially treated with: a low cholesterol, fat restricted
diet; diet and probucol (500 mg/day); and diet, probucol and
niceritrol (1500 mg/day).
Concentrations of plasma cholesterol decreased from 348 + 49 mg/dl on
diet alone to 304 + 32 mg/dl, to 256 + 30 mg/dl on diet and probucol,
and fell to 212 + 41 mg/dl on the combined regimen with niceritrol.
Concentrations of LDL-cholesterol declined 13% on diet, and 26% on
diet and probucol; the subsequent addition of niceritrol resulted in a
42% fall from the baseline.
Plasma concentrations of apolipoprotein B fell 37% on the combined
regimen with niceritrol.
As a result, normal levels of cholesterol (less than 230 mg) were
achieved in thirteen subjects treated with this new combination
therapy.
Moreover, atherogenic index improved with the addition of niceritrol.
These results suggest even a small dose of niceritrol affords
opportunity to maintain normal lipid profile in heterozygous familial
hypercholesterolemia when given in combination with probucol.
Review References: None
Notes: None
Language: English
Publication Type: Journal-Article
Keywords: Hypercholesterolemia, Familial drug therapy : Niceritrol
therapeutic use : Probucol therapeutic use

----------------------------------

http://tinyurl.com/ynpdhm

"Iron-chelating agents, N-acetyl-L-cysteine (NAC), apocynin,probucol,
and edaravone, are useful in preventing cardiovascular injury and
diseases."

Recent Patents on Anti-Infective Drug Discovery, 2006, 1,
17-31171574-891X/06 $100.00+.00(c) 2006 Bentham Science Publishers
Ltd.Recent Progress in Pharmacological Research of Antioxidants
inPathological Conditions: Cardiovascular Health

Who loves ya.
Tom

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http://jesuswasavegetarian.7h.com

Man Is A Herbivore!
http://tinyurl.com/a3cc3

DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

.
lily - 15 Mar 2008 14:54 GMT
As you all are much aware about the effectiveness of 'Yoga' and also
practice it regularly, so I want to share a site with you all. When
going the alternative medicine route one is often left to research and
experiment to find the right products and resources. Here is a new
site that is beginning to gather all the resources in one place. You
can research conditions for various therapeutic modes, including
Ayurvedic medicine, and get information about the effectiveness of
therapies and remedies. The site is also a launching point for
researching integrated alternative medicine therapies on the web. Go
to http://www.rvita.com  .  Hope it will help you to gather more
knowledge about 'Yoga' and other things.
 
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