 |
 | Home | Contact Us | FAQ | Search & Site Map | Link to Us |
 | Sign In | Join | Other 45 Sites in Network |
Medical Forum / General / Alternative / September 2005Vitamin C improves the outcome of schizophrenia
Psychopharmacology (Berl). 2005 Aug 13;:1-5 [Epub ahead of print] Links Supplementation of vitamin C with atypical antipsychotics reduces oxidative stress and improves the outcome of schizophrenia. Dakhale GN, Khanzode SD, Khanzode SS, Saoji A. Department of Pharmacology, Government Medical College, Nagpur, India. RATIONALE: Several investigators implicated role of free radical-mediated pathology in schizophrenia. No study has ever examined the effect of vitamin C with atypical antipsychotics in the treatment of schizophrenia. OBJECTIVE: The aim of this study was to examine the effect of oral vitamin C with atypical antipsychotics on serum malondialdehyde (MDA), plasma ascorbic acid levels, and brief psychiatric rating scale (BPRS) score in schizophrenic patients. METHOD: Forty schizophrenic patients participated in a prospective, double-blind, placebo-controlled, noncrossover, 8-week study. The patients with schizophrenia were divided randomly into placebo and vitamin C group of 20 each. Serum MDA and plasma ascorbic acid were estimated by methods of Nischal and Aye, respectively. RESULT: Increased serum MDA and decreased plasma ascorbic acid levels were found in schizophrenic patients. These levels were reversed significantly after treatment with vitamin C along with atypical antipsychotics compared to placebo with atypical antipsychotics. BPRS change scores at 8 weeks improved statistically significant with vitamin C as compared to placebo. CONCLUSION: Oral supplementation of vitamin C with atypical antipsychotic reverses ascorbic acid levels, reduces oxidative stress, and improves BPRS score, hence both the drugs in combination can be used in the treatment of schizophrenia. PMID: 16133138 [PubMed - as supplied by publisher] -------------------------------------------------------------------------------- Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking > Supplementation of vitamin C with atypical antipsychotics reduces > oxidative stress and improves the outcome of schizophrenia. What are you saying? Does that mean that there is hope for you and the rest of this ng? If so, what are you waiting for? If NOT, does that not tend to prove that this study is wrong? What is your problem? You have my condolences. What are you saying? << http://members.aol.com/pbchowka/hoffer.html <<snip>> HOFFER: When our work on schizophrenia was first published in 1957, ... I simply modified her program and suggested she take as much vitamin C as she could .. <<snip>> Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking > HOFFER: When our work on schizophrenia was first published in 1957, ... > I simply modified her program and suggested she take as much vitamin C > as she could .. HOFFER A??? Just like your above quote, PubMed documents that all of his serious work was done back in the dark ages, ie before 1965. That fossile Hoffer had a ghostwriten paper published in 2004, a book review in '89 (Ha, ... Hah, Ha!), then his "Orthomolecular treatment of schizophrenia" in 1973. You are an idiot. Just thought that you might want to know. |
Reply to this Message |
 Sign In
 Join
 My Latest Posts My Monitored Threads My Blog My Photo Gallery My Profile My Homepage Start New Thread Enable EMail Alerts Rate this Thread
|
©2009 Advenet LLC Privacy Policy - Terms of Use
This website includes both content owned or controlled by Advenet as well as content owned or controlled by third parties.