overma...@hotmail.com wrote:
> Over my head, could we get a translation?
>
> Also, what do you make of the fact that Wormser et al did not find B.
> lonestari in blood samples from Master's patients? Is this because the
> thing the Worm does best is not find disease agents?
They knew Master's disease was a bovine borreliosis since May 2000.
http://jcm.asm.org/cgi/content/full/39/2/494/F1
Here is Wormser acting like he didn't know:
Clin Infect Dis. 2005 Feb 1;40(3):423-8. Epub 2005 Jan 10. Related
Articles, Links
Click here to read
Microbiologic evaluation of patients from Missouri with erythema
migrans.
Wormser GP, Masters E, Liveris D, Nowakowski J, Nadelman RB,
Holmgren D, Bittker S, Cooper D, Wang G, Schwartz I.
Division of Infectious Diseases, Department of Medicine, New York
Medical College, Valhalla, NY 10595, USA. gary_wormser@nymc.edu
BACKGROUND: Borrelia lonestari infects Amblyomma americanum, the
tick species that is the most common cause of tick bites in southeast
and south-central United States, and this spirochete has been detected
in an erythema migrans (EM)-like skin rash in 1 patient. Therefore, B.
lonestari is considered to be a leading candidate for the etiologic
agent of EM in this region. METHODS: Skin biopsy specimens obtained
from patients from the Cape Girardeau area of Missouri who had EM-like
lesions were cultured in Barbour-Stoenner-Kelly medium and evaluated by
polymerase chain reaction (PCR) targeting multiple genes. Serum
specimens were tested by enzyme-linked immunosorbent assay for
antibodies against sonicated whole-cell Borrelia burgdorferi. Results
were compared with those obtained over the same period for patients
from New York State who had EM. RESULTS: B. lonestari was not detected
by PCR in any of 31 skin biopsy specimens collected from 30 Missouri
patients. None of 19 cultures of Missouri skin samples that were
suitable for evaluation were positive for B. burgdorferi, compared with
89 (63%) of 142 cultures of samples collected from New York State
patients (P<.001). None of the 25 evaluable Missouri patients were
seropositive for antibodies against B. burgdorferi, compared with 107
(75%) of 143 New York State patients (P<.001). CONCLUSIONS: Neither B.
lonestari nor B. burgdorferi is likely to be the cause of EM-like skin
lesions in patients from the Cape Girardeau area of Missouri. The
etiology of this condition remains unknown.
PMID: 15668867 [PubMed - in process]