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Medical Forum / General / Alternative / May 2005

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Chemotherapy in early breast cancer

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Peter Moran - 21 May 2005 23:18 GMT
I confess to having a suspicion that chemotherapy was being used too readily
in early breast cancer in some quarters, especially the US.   I was wrong.

A recently published meta-analysis of fifteen year results in the Lancet
shows that -

"Allocation to about 6 months of anthracycline-based polychemotherapy (eg,
with FAC or FEC) reduces the annual breast cancer death rate by about 38%
(SE 5) for women younger than 50 years of age when diagnosed and by about
20% (SE 4) for those of age 50-69 years when diagnosed, largely irrespective
of the use of tamoxifen and of oestrogen receptor (ER) status, nodal status,
or other tumour characteristics."

Effects of chemotherapy and hormonal therapy for early breast cancer on
recurrence and 15-year survival: an overview of the randomised trials M
Clarke, R Collins, S Darby, C Davies, et al. The Lancet. London: May 14-May
20, 2005.Vol.365, Iss. 9472; pg. 1687

Kinda demolishes the alt.med canard that chemotherapy makes it harder to
deal with the cancer through immune system impairment.

Peter Moran
LadyLollipop - 22 May 2005 00:43 GMT
>I confess to having a suspicion that chemotherapy was being used too
>readily in early breast cancer in some quarters, especially the US.   I was
[quoted text clipped - 19 lines]
>
> Peter Moran

Yeah, chemo is very good for the immune system, it hardly kills anything.

Sure thing, Peter.

LL/Jan
Peter Moran - 22 May 2005 04:57 GMT
>>I confess to having a suspicion that chemotherapy was being used too
>>readily in early breast cancer in some quarters, especially the US.   I
[quoted text clipped - 25 lines]
>
> LL/Jan

And your point?

Jan, in what way does dying earlier or more often from breast cancer if you
*don't* have chemotherapy demonstrate a more robust immune system?

Peter Moran

.
George  Lagergren - 22 May 2005 13:19 GMT
> Jan, in what way does dying earlier or more often from breast cancer if you
> *don't* have chemotherapy demonstrate a more robust immune system?

           Maybe women who don't have chemotherapy will live longer since
their immune system is not damaged by it.
Mark Probert - 22 May 2005 16:39 GMT
George Lagergren wrote:

>>Jan, in what way does dying earlier or more often from breast cancer if
>
[quoted text clipped - 4 lines]
>             Maybe women who don't have chemotherapy will live longer since
> their immune system is not damaged by it.

Maybe if you read Peter's original post you would see that you are wrong.
David Wright - 22 May 2005 23:14 GMT
>> Jan, in what way does dying earlier or more often from breast cancer if
>you
>> *don't* have chemotherapy demonstrate a more robust immune system?
>
>         Maybe women who don't have chemotherapy will live longer since
>their immune system is not damaged by it.

Ah, George -- you're so unhobbled by reading comprehension.

 -- David Wright :: alphabeta at prodigy.net
    These are my opinions only, but they're almost always correct.
      "I don't need someone to tell me that George W. Bush is a
       deceitful, corrupt, clever and destructive man--that's pretty
       clear on the face of it."  -- Garrison Keillor
D. C. Sessions - 22 May 2005 23:54 GMT
George Lagergren wrote:

>>Jan, in what way does dying earlier or more often from breast cancer if
>
[quoted text clipped - 4 lines]
>             Maybe women who don't have chemotherapy will live longer since
> their immune system is not damaged by it.

Maybe indeed.  If you go back to the thread root, PM harbored
that same suspicion.  Facts came along an proved him wrong:
chemotherapy for breast cancer increases survival across the
board, as measured by actual survival in a prospective study.

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Mark Probert - 22 May 2005 16:38 GMT
>>I confess to having a suspicion that chemotherapy was being used too
>>readily in early breast cancer in some quarters, especially the US.   I was
[quoted text clipped - 23 lines]
>
> Sure thing, Peter.

Another excellent example of Jan not reading what Peter posted. Clearly,
the study, which is scientific and not ilde speculation, demonstrates
that chemo before surgery prolongs life. Jan does not want any part of
prolonging life.

BTW, Jan, does all chemo affect the immune system?
drceephd2@netscape.com - 24 May 2005 02:03 GMT
>Kinda demolishes the alt.med canard that chemotherapy makes it harder to
deal with the cancer through immune system impairment.

>Peter Moran

I suggest that you study the report in more detail.

Giving poison A may reduce the recurrance of cancer relative to poison
B but this data is confounded by too many patients dying is what I see.

The above referenced meta analysis in no wise alters the obvious
results of chemo.

As a scientist and chemist, I tend to trust the data published by the
ACS, the American Chemical Society.  As a nutritionist, I look at the
published nutritional data with some scepticism.  I still view medical
journals as a published lie especially when the spin is put on the
results that one can poison the sick into getting well, and that some
of the most poisonus chemicals can be beneficial to humans as far as
the death rate is concerned.

DrC PhD
David Wright - 26 May 2005 03:20 GMT
>>Kinda demolishes the alt.med canard that chemotherapy makes it harder
>>to deal with the cancer through immune system impairment.
[quoted text clipped - 5 lines]
>Giving poison A may reduce the recurrance of cancer relative to poison
>B but this data is confounded by too many patients dying is what I see.

You see what you want to see, due to your own severe biases.

>The above referenced meta analysis in no wise alters the obvious
>results of chemo.

Sure it does.  You just don't like the conclusions, so you'll pull
your usual trick of sticking your fingers in your ears and screaming
that there's no good evidence.

>As a scientist and chemist, I tend to trust the data published by the
>ACS, the American Chemical Society.

I doubt you're much of a chemist.  You're definitely no scientist.
Scientists go where the data sends them, whether they like the
destination or not.  You are simply a religious fanatic who will
reject any data that fails to fit your weltanschauung.

>As a nutritionist, I look at the published nutritional data with some
>scepticism.

As a nutritionist, you make a good religious fanatic.  The only data
you accept are from orthopaths who've been dead for a century.

>I still view medical journals as a published lie especially when the
>spin is put on the results that one can poison the sick into getting
>well, and that some of the most poisonus chemicals can be beneficial
>to humans as far as the death rate is concerned.

Unless, of course, the medical journal happens to publish an article
that you agree with.  Then it's OK.

 -- David Wright :: alphabeta at prodigy.net
    These are my opinions only, but they're almost always correct.
      "I don't need someone to tell me that George W. Bush is a
       deceitful, corrupt, clever and destructive man--that's pretty
       clear on the face of it."  -- Garrison Keillor
 
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