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Medical Forum / Diseases and Disorders / AIDS / October 2006Already infected?
I had unprotected sex with my boyfriend over the weekend. he is hiv + but he is untectectable. It has been five days and I'm having diarrhea. Do HIV effects show up this early? Thanks, Kathy Though my view is different in some ways that may be considered important from an academic or technical perspective, I suggest you watch the following video on google: http://video.google.com/videoplay?docid=-4396856850556632563&q=HIV+Fact+or+Fiction >I had unprotected sex with my boyfriend over the weekend. he is hiv + but >he is untectectable. It has been five days and I'm having diarrhea. Do HIV >effects show up this early? Thanks, Kathy The only way to find out is to go to a hospital and get tested. Let them know it is VERY recent exposure so they will do a viral load test. George M. Carter thank you everyone, but how can the tests show a viral load? I thought I had to wait at least 4 weeks? Thank you, Mr. Carter. kathy >>I had unprotected sex with my boyfriend over the weekend. he is hiv + but >>he is untectectable. It has been five days and I'm having diarrhea. Do [quoted text clipped - 6 lines] > > George M. Carter > thank you everyone, but how can the tests show a viral load? <snort> I have no doubt where this is one suddenly going to go. B/ what do you mean, brian? >> thank you everyone, but how can the tests show a viral load? > [quoted text clipped - 3 lines] > > B/ "Brian Mailman" <bmailman@sfo.invalid> wrote in message > I have no doubt where this is one suddenly going to go. > > Thank you, Mr. Carter. >thank you everyone, but how can the tests show a viral load? I thought I >had to wait at least 4 weeks? Thank you, Mr. Carter. The initial infection does not immediately result in the development of antibodies. That takes a few weeks generally. However, if you have a high viral load, the PCR test can detect that and establish if you have been exposed. George M. Carter Thank you, George. I have an appointment to get my blood work done this morning. If it comes back that I have been exposed do that automatically mean that I will be HIV +? Sorry for all the questions. At least these "flu" like symptoms only lasted a day.... Kathy >>thank you everyone, but how can the tests show a viral load? I thought I >>had to wait at least 4 weeks? Thank you, Mr. Carter. [quoted text clipped - 6 lines] > > George M. Carter >Thank you, George. I have an appointment to get my blood work done this >morning. > >If it comes back that I have been exposed do that automatically mean that I >will be HIV +? Not automatically. However, if the viral load comes back high (perhaps over 5000), the chances may be strong that your immune system will develop the antibodies that indicates HIV+ status. If the viral load is a lower figure, it may mean that you were infected but it may be a test error. >Sorry for all the questions. At least these "flu" like symptoms only lasted >a day.... That is encouraging but not definitive. I wish you the best of luck--and hope that you'll be sure to have your boyfriend use condoms! Latex with water-based lube or polyurethane. George M. Carter Something else to consider below. George M. Carter **** New Test for Acute HIV Infection FDA Approved The Food and Drug Administration (FDA) announced the approval, on October 5, 2006, of the APTIMA(r) HIV-1 RNA Qualitative Assay, manufactured by Gen-Probe Incorporated of San Diego, California, for use in clinical laboratories and public health facilities to detect primary (early) HIV-1 infection. The APTIMA~ HIV-I RNA Qualitative Assay is an in vitro nucleic acid test (NAT) for the detection of human immunodeficiency virus (HIV-1) in human plasma intended for use as an aid in the diagnosis of HIV-I infection, including acute or primary infection, before the appearance of antibodies to HIV-1. Traditional detection and diagnosis of HIV-I infection is based on testing for anti-viral antibodies by enzyme immunoassay (EIA) with confirmation by supplemental antibody tests such as Western blot or immunofluorescence assays (IFA). Although sensitivity of HIV-1 antibody detection has increased in the last few years, a window period between infection and detectable serological markers still exists. Following a recent exposure to HIV-I, it may take several months for the antibody response to reach detectable levels, during which time, testing for antibodies to HIV-I, including the use of rapid antibody tests, will not indicate true infection status. The newly approved test may provide earlier diagnosis of infection because it detects nucleic acid of the human immunodeficiency virus (HIV-1) in human plasma, rather than the antibody response to the virus. Presence of HIV-I RNA in the plasma of patients without antibodies to HIV-I is indicative of acute or primary HIV-1 infection. The test, however, is not meant to be used as a stand-alone test for the diagnosis of HIV-1 infection. A positive nucleic acid test should be viewed as a unconfirmed test result, indicating probable infection, and should be followed up later with traditional EIA antibody testing to confirm infection with the Human Immunodeficiency Virus. In addition, the APTIMA HIV-1 RNA Qualitative Assay may be used as an additional test to confirm HIV-I infection in an individual whose specimen is repeatedly reactive for HIV-1 antibodies. This is important because the Western blot can, in some instances, be difficult to interpret and may not always provide a conclusive result. The APTIMA test can be used instead of the traditional Western blot test or IFA for confirmation of HIV-1 infection when the screening test result for HIV-1 antibodies is positive. The sensitivity of the APTIMA(r) HIV-1 RNA Qualitative Assay is comparable to that of FDA approved viral load assays that measure the amount of HIV-1 virus circulating in the blood of patients with established HIV-1 infection to monitor the treatment and progression of AIDS. Unlike the viral load tests, however, the APTIMA test has been approved for the diagnosis of primary HIV-1 infection, as well as for confirming HIV-1 infection when tests for antibodies to HIV-1 are positive. The product labeling for this test will be available soon on the list of FDA Licensed / Approved HIV, HTLV and Hepatitis Tests on the FDA web site. Richard Klein Office of Special Health Issues Food and Drug Administration > I had unprotected sex with my boyfriend over the weekend. he is hiv + but > he is untectectable. It has been five days and I'm having diarrhea. Do HIV > effects show up this early? Thanks, Kathy from drdach.com I would suggest you pay a visit to your trusted family doctor who can sort this out for you. For further discussion on this topic or any other, please visit my web site and leave a comment on the contact page. regards from www.drdach.com > For further discussion on this topic or any other, please visit my web > site and leave a comment on the contact page. Kathy, I advise seeing your own medical practitioner of contacting a genito-urinary clinic for a discussion/advice. However, I don't think you need to visit Dr Dach's web page (at least not unless you wish to avail yourself of the services or advice of an "anti-aging specialist". You sound far too young in my opinion). > > For further discussion on this topic or any other, please visit my web > > site and leave a comment on the contact page. [quoted text clipped - 5 lines] > not unless you wish to avail yourself of the services or advice of an > "anti-aging specialist". You sound far too young in my opinion). reply from drdach: David T is an anonymous web surfer with no web site and no identity which, as you know, is associated with zero credibility. Please feel free to visit my web site anytime. regards from www.drdach.com >reply from drdach: > [quoted text clipped - 3 lines] > >Please feel free to visit my web site anytime. Why the f.ck should anyone bother when you're so remarkably ignorant of the subject upon which you claim to have some expertise??? First of all why are you having unprotected sex if you know he is HIV+ The only way to know for sure is to get HIV tested now, in 6 weeks, 3 months and finally in 6 months. If all those tests are negative and you have no further unprotected exposures, you are negative. Please...use a condom...it only takes one time to be infected. > I had unprotected sex with my boyfriend over the weekend. he is hiv + but > he is untectectable. It has been five days and I'm having diarrhea. Do HIV > effects show up this early? Thanks, Kathy Kathy wrote... > I had unprotected sex with my boyfriend over the weekend. he is hiv + but > he is untectectable. It has been five days and I'm having diarrhea. Do HIV > effects show up this early? Thanks, Kathy I never heard of gastrointestinal effects from HIV infection, it typically resembles a cold, flu, or general body infection (aches, chills, etc.). You might have escaped infection this time, but I am going to lecture you on how incredibly stupid you are to remain with an HIV+ partner. Just the fact that your boyfriend was stupid enough to catch the virus shows what a fucktarded loser he is; I can't imagine what personality traits can possibly compensate for the risk of dying every time you have sex with him. I know someone who purports to be HIV- who is in a relationship with someone who is HIV+. He thinks he is safe because they always (usually?) use condoms when f.cking each other and the several other tweeked-out dog turds they drag home from the gay bar for orgies where they inject crystal meth into their rectums with turkey basters. It's nice to think about how my tax money will go towards the million dollars a year it costs to treat him when he finally tests HIV+. I took my test; they said it will take seven days. They said even though my boyfriend's viral load in the BLOOD is undetectable, his semen might be high. I wish there were a way to test the semen to see if he was undetectable in the semen. Has anyone heard of a semen level being high while the blood level is low or vice versa? Kathy Even though you've been "rough" on me, your advice is much needed at this time... > Kathy wrote... >> I had unprotected sex with my boyfriend over the weekend. he is hiv + [quoted text clipped - 22 lines] > finally > tests HIV+. "Kathy" <KathyG@hotmail.com> wrote in message > I took my test; they said it will take seven days. LOL, I need to start calling yall... hook, line and sinker. "GMCarter" <fiar@verizon.net> wrote in message "Brian Mailman" <bmailman@sfo.invalid> wrote in message "jdach" <drdach@drdach.com> wrote in message >I took my test; they said it will take seven days. > >They said even though my boyfriend's viral load in the BLOOD is >undetectable, his semen might be high. I wish there were a way to test the >semen to see if he was undetectable in the semen. Has anyone heard of a >semen level being high while the blood level is low or vice versa? Yes. Viral load can be higher than in blood--it depends partly on whether the antiviral regimen he is on penetrates that compartment. Testing, though, of semen is only done in a research setting, not as a routine test. George M. Carter "GMCarter" <fiar@verizon.net> wrote in message > Yes. Viral load can be higher than in blood--it depends partly on > whether the antiviral regimen he is on penetrates that compartment. > > Testing, though, of semen is only done in a research setting, not as a > routine test. Michael Carter, Tuesday, December 06, 2005 The shedding of cytomegalovirus (CMV) in the genital tract is associated with a higher HIV viral load in semen, according to a small Canadian study published in the January 1st 2006 edition of the Journal of Infectious Diseases (now online). HIV viral load in semen is strongly associated with viral load in blood. Although the amount of HIV in semen is generally lower than in blood, some men shed disproportionately large amounts of HIV in their semen, and many men who have low HIV levels in their semen have intermittent "spikes" in HIV viral load in their semen. Increased shedding of HIV in semen has been associated with sexually transmitted infections. Although not classified as a sexually transmitted infection, CMV can be readily transmitted during sex and earlier studies have suggested that CMV is present in also present in the semen of men shedding large amounts of HIV in their genitals. To gain a better understanding of the role of CMV activation in the genitals on HIV viral load in semen, investigators from Toronto obtained paired blood and semen samples from 26 HIV-positive men. All the men had been infected with HIV for over six months, none were taking antiretroviral therapy, and all had tested negative for sexually transmitted infections including gonorrhoea and Chlamydia. All 26 men were gay and all were infected with CMV. Median CD4 cell count was 574 cells/mm3 and median HIV viral load in blood was 21,400 copies/ml. CMV was not detected in the blood of any of the men, but was being shed in the semen of 17 (65%). Although men shedding CMV in their genitals had a lower median CD4 cell count than those who were not (509 cells/mm3 versus 696 cells/mm3), there was no difference in their HIV viral load in blood. Overall, median HIV viral load was higher in blood than in semen (20,000 copies/ml vs 5,000 copies/ml), but the investigators found that in nine men (35%) more HIV was being shed in semen than in blood. These nine men were defined as "disproportionately high semen HIV shedders" and their median blood HIV viral load was a little under 22,000 copies/ml and their median semen HIV viral load was 48,000 copies/ml. CMV was detected in the semen of all nine men who were shedding disproportionately large amounts of HIV in their semen, but was only found in the semen of eight of the other 17 men who had more HIV in their blood than semen. This difference was statistically significant (p = 0.002). The investigators also found that the mean CMV viral load in semen was over 100 fold greater in the men shedding disproportionately large amounts of HIV in their genitals. The investigators also found a correlation between semen HIV load and the level of CMV shedding in the genitals (p = 0.05). Further tests were performed by the investigators which indicated that CMV activation discreet to the genital tract was causing HIV viral load to be disproportionately increased in the semen of the nine men. Tests were also performed to see if infection with herpes simplex virus-2 (HSV-2) increased HIV viral load in the genital tract. However, no relationship was found between infection with HSV-2 and disproportionately high shedding of HIV, even when CMV shedding was included in the analysis. "We have confirmed that the presence of CMV in semen is associated with increased likelihood of HIV shedding", write the investigators. They add, "more importantly, we have demonstrated that disproportionate shedding of HIV in semen, relative to that in blood, is strongly associated with local CMV reactivation in the male genital tract.these observations emphasize the potential for very substantial negative synergy between these two infections." The investigators' findings could have very important implications for HIV prevention. Men with increased shedding of HIV in their genitals due to CMV are likely to be considerably more infectious for HIV and the investigators conclude, "prevention of CMV reactivation warrants study as a possible strategy to reduce semen shedding of HIV." Reference Sheth PM et al. Disproportionately high semen shedding of HIV is associated with cytomegalovirus reactivation. J Infect Dis 193 (online edition), 2006. > I had unprotected sex with my boyfriend over the weekend. he is hiv + but > he is untectectable. It has been five days and I'm having diarrhea. Do HIV > effects show up this early? Thanks, Kathy reply from drdach: Appearance of HIV Antibodies After Exposure, and HIV Testing to Determine Status: A human immunodeficiency virus (HIV) test detects antibodies to HIV in the blood. After the original exposure, it takes between 2 weeks and 6 months for antibodies to HIV to appear in the blood. The period between exposure and the time when antibodies to HIV can be detected is called the seroconversion or "window" period. During this period, an HIV-infected person can transmit the HIV virus, even though a test will not detect any antibodies. Several tests can find antibodies or genetic material (RNA) to the HIV virus. These tests include: Enzyme-linked immunosorbent assay (ELISA). This test is usually the first one used to detect HIV antibodies. If antibodies to HIV are present (positive), the test is usually repeated to confirm the diagnosis. If ELISA is negative, no further testing needed. This test has a low chance of having a false result after the first few weeks that a person is infected. Western blot. This test is more difficult than the ELISA to perform, but it is done to confirm the results of two positive ELISA tests. Polymerase chain reaction (PCR). This test finds either the genetic material DNA or RNA of HIV. PCR testing is not done as frequently as antibody testing because it requires technical skill and expensive equipment. This test may be done in the days or weeks after exposure to the virus. Genetic material may be found even if other tests are negative for the virus. Testing is often done at 6 weeks, 3 months, and 6 months after exposure to determine that a person is not infected. For more HIV causes AIDS information, see these web sites below: (Note: inclusion here does not imply endorsement by the management ) The Body is a Web site where you can receive answers to questions posed to M.D.'s trained in HIV diagnosis and treatment. The site is maintained by major drug companies and lab testing companies. http://www.thebody.com/index.html HIV information site funded by Boehringer Ingelheim (Drug Company Orthodox Views) http://www.aegis.com/pubs/atn/ Steve Harris MD: strong proponent of HIV causes AIDS hypothesis: he also believes harmless the practice of inhaling poppers (alkyl butyl nitrate drugs used by homosexuals to enhance sexual experiences) http://www.virusmythpoppersmyth.org/steve_harris_md/ http://www.virusmythpoppersmyth.org/cause_of_aids/ AIDStruth web site: funded by TAG, Treatment Action Group, HealthGAP, AIDS and Rights Alliance for Southern Africa (Includes recent essay about the JAMA Sept 27 2006 article by authors Rodriguez and Lederman ) http://www.aidstruth.org/ AIDSmeds.com was founded by Peter Staley in 1999 founding member of ACT UP New York. In 1992, Peter founded the Treatment Action Group (TAG). http://www.aidsmeds.com/ NIH web site: The Evidence That HIV Causes AIDS http://www.niaid.nih.gov/factsheets/evidhiv.htm http://www.niaid.nih.gov/publications/hivaids/hivaids.htm http://www3.niaid.nih.gov/news/focuson/hiv/resources/default.htm AVERT is an international HIV and AIDS charity based in the UK http://www.avert.org/evidence.htm Information on the Western Blot Test http://www.westernblotting.org/ Electron Microscope Images thought to be HIV particles http://www.virology.net/Big_Virology/BVretro.html TextBook of AIDS Pathology : Edward C. Klatt, MD, Florida State University College of Medicine July 31, 2006, "About 10% of persons infected with HIV-1 are nonprogressors, or "long survivors," who do not demonstrate a significant and progressive decline in immune function over more than 10 years. They do not appear to progress to AIDS in a manner similar to the majority of HIV-infected persons. Findings in these "long survivors" include: a stable CD4 lymphocyte count," http://library.med.utah.edu/WebPath/AIDS2006.PDF For the sake of completeness and balance, I have included web sites below which offer opposing viewpoints to the hypothesis that HIV Causes AIDS. These are for more adventurous thinkers: (Note: inclusion here does not imply endorsement by the management ) VirusMyth - a site run by Robert Laarhoven documenting the HIV/AIDS controversy www.virusmyth.com Health Education AIDS Liaison (HEAL), Toronto www.healtoronto.com The Group for the Scientific Reappraisal of the HIV-AIDS Hypothesis http://rethinkingaids.com/ AIDSMYTH is a global-reach voluntary group whose goal is ensuring the interests of Aids-diagnosed people are no longer secondary to the interests of drug suppliers, service providers and the Aids research industry. http://aidsmyth.addr.com/ ACT UP San Fransisco http://www.actupsf.com/ Mothering Magazine: HIV info for pregnant mothers: http://www.mothering.com/ Safe and Sound Underground: HIV-Positive Women Birthing Outside the System By Susan Gerhard Issue 108, September/October 2001 http://www.mothering.com/articles/new_baby/breastfeeding/hiv-underground.html The web site of Dr. Peter Duesberg, one of the original AIDS dissidents. www.duesberg.com David Crowe's Alberta Reappraising AIDS Society www.aras.ab.ca Christine Maggiore's Alive and Well AIDS Alternatives www.aliveandwell.org Roberto Giraldo's web site, featuring a wealth of AIDS information in both Spanish and English www.robertogiraldo.com The Website of Dr. Jonathan Fishbein, the FDA whistleblower on corruption in AIDS Drug Research www.honestdoctor.org The official site for the documentary: The Other Side of AIDS, by Robin Scovill. www.theothersideofaids.com Prof. Robert C. Gallo, M.D., inventor of the AIDS virus. http://www.sparks-of-light.org/galloframeset.htm Deane's World Blog http://www.deanesmay.com/posts/1104249710.shtml Nice Compilation of all discussions: http://www.suppressedscience.net/aids Video on HIV/AIDS: FACT or FICTION? Interviewed in this program are Dr. Peter Duesberg, Dr. Charles Thomas who initiated the group for Scientific Reappraisal of HIV, http://video.google.com/videoplay?docid=-4396856850556632563&q=HIV+Fact+or+Fiction The Controversy over HIV and AIDS Science correspondent Jon Cohen , Volume 266 - 9 December 1994 http://www.sciencemag.org/feature/data/cohen/cohen.dtl Fumento believes that HIV causes AIDS so maybe should have been placed above. Placed here because he disbelieves in the "heterosexual AIDS epidemic" that never happened. The Myth of Heterosexual AIDS, How A Tragedy Has Been Distorted by the Media and Partisan Politics By Michael Fumento http://www.fumento.com/suaids.html Regards from www.drdach.com |
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