My brother is visiting for a couple of weeks and I can't stand it.
He's been HIV+ probably since around 1991 (symptoms appeared in
1994), and the extra 10 years the new drugs gave him were wasted on
crystal meth and the gay bar and all its tweeked-out HIV+ twinkies.

So now he's literally a raving lunatic, already involuntarily
committed until the hospital had to evict him for lack of funds,
and my family is stuck with him.  He can't work, he smokes a
carton of tobacco cigarettes a day (he actually lights a new
cigarette within 5 minutes of finishing the last!), rambles on
incoherently about the weirdest sh.t, and harasses his so-called
friends on the phone (using my long distance).  He is suffering
serious delusions, one being that he is blackmailing one of
"good friends" because he had confessed to killing his boyfriend.
This is especially irritating, because although I didn't really
like the guy, he was nice enough and had stuck by my brother
through the worst of his insanity and now my brother turns on him
and accuses him of murder (there's no evidence of a death, I
think the boyfriend simply left my brother's friend).

Oh, and while I don't subscribe to traditional religious morality,
I am fairly ethical and my brother irritates me because he is
ethically BANKRUPT.  He has absolutely no conception of what is
fair and honest and what is not.  One example is last year after
I finished babysitting him.  He had ripped off a "good friend" to
get money (he is broke and I was controlling his money supply),
the friend forgave him and was driving my brother somewhere and
his raving caused the guy to run a red light and hit another car.
My brother insisted on being taken to the hospital by ambulance,
the hospital determined he was uninjured and released him, my
brother went to the gay bar and bought some crystal meth from the
fag hag who sits there all night long selling it, and proceeded
to attack his neighbor's car with a vacuum cleaner.  Naturally,
this was all the fault of the hospital and he hired a lawyer to
sue them and I think their angle was going to be that the
trauma of the accident had induced PTSD in my brother which the
hospital failed to diagnose; I put a stop to that with a letter to
the hospital's legal department, but he just got a $2700 settlement
from the friend's insurance company (I'm going to complain to the
state insurance commission).  The $2700 quickly went up his nose
and now he is insaner than ever.  All the drivers in Nevada should
be so happy that they now have to pay higher premiums to settle
nuisance lawsuits filed by mentally-ill crackheads.