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Medical Forum / Diseases and Disorders / AIDS / December 2003

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HIV transmission and testing

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Curious - 02 Dec 2003 04:46 GMT
About 3 weeks ago I had a brief unprotected sexual encounter (I am a
male). There was approximately 5 seconds of unprotected
contact/penetration. I do not know who the woman is so I will be
unable to see her again. I do not know if she has HIV but I am
concerned about possible transmission.

I am curious about the risks of having contracted HIV. I did not have
any STDs or open sores or anything on my penis. Although I was
concerned I may have caught something based on some pains I was having
so the doctor gave me some antiobiotics and things seem basically back
to normal. How much contact and what types of physical environment
(e.g. open sores) is required for HIV transmission?

What is the normal timeline after possible transmission before getting
an HIV
test?
Gil - 02 Dec 2003 20:04 GMT
>About 3 weeks ago I had a brief unprotected sexual encounter (I am a
>male). There was approximately 5 seconds of unprotected
[quoted text clipped - 12 lines]
>an HIV
>test?
glutathion - 03 Dec 2003 12:12 GMT
> About 3 weeks ago I had a brief unprotected sexual encounter (I am a
> male). There was approximately 5 seconds of unprotected
[quoted text clipped - 12 lines]
> an HIV
> test?

From the french health ministery :

http://www.sante.gouv.fr/pdf/dossiers/sidahop/ch16.pdf  p 202 :

RAPPORT SEXUEL NON PROTÉGÉ AVEC UNE PERSONNE SÉROPOSITIVE
UNPROTECTED INTERCOURSE WITH A SEROPOSITIVE INDIVIDUAL

** ppa = probabilité de transmission par acte. (transmission
probability for one intercourse)

2. Vaginal réceptif : ppa [0,3 ‰–0,7 ‰]
3. Vaginal insertif* : ppa [0,2 ‰–0,5‰]
Curious - 04 Dec 2003 15:14 GMT
Thanks for the responses. If I'm reading this right it appears to be
good news, if the person was infected. I just need to be smarter and
more responsible in the future to avoid situations such as this. I've
been an anxiety nightmare in my head the past few weeks. I'm trying to
just get some info, take a deep breath and then get myself tested at
some point in the near future. What is the typical time before a test
should be taken? I did some reading about there being window periods
when the infection may or may not show up.

> From the french health ministery :
>
[quoted text clipped - 8 lines]
> 2. Vaginal réceptif : ppa [0,3 ??0,7 ?]
> 3. Vaginal insertif* : ppa [0,2 ??0,5?]
Brian Mailman - 04 Dec 2003 16:07 GMT
> Thanks for the responses. If I'm reading this right it appears to be
> good news, if the person was infected. I just need to be smarter and
> more responsible in the future to avoid situations such as this.

Cool.  Seems you've heard the wakeup call!

> ... What is the typical time before a test
> should be taken? I did some reading about there being window periods
> when the infection may or may not show up.

Earliest test should be 3 months/12 weeks after possible exposure.  Then
another at six months, which should catch 99.9% of infections.

If you're still concerned, a third six months after that.

Someone may counsel you to agitate for a "DNA" test.  Don't.  It's my
understanding those are _too_ sensitive and can report a false
positive.  Diagnosis is not what they're designed for, it's like using a
pregnancy test to detect uterine cancer.

B/
Gary Stein - 04 Dec 2003 16:37 GMT
> > Thanks for the responses. If I'm reading this right it appears to be
> > good news, if the person was infected. I just need to be smarter and
[quoted text clipped - 17 lines]
>
> B/

Brian while PCR is indeed not labeled as a diagnostic test, it has become
the standard of care in labs, and hospitals when dealing with one of there
staff who has had a needle stick incident. So it is unfair to label it as
not mainstream for the early detection of HIV in patients who are part of
the medical community. In these cases early detection is thought to be
critical in assessing the patients need for an Anti-retroviral drug
treatment plan. With this type of early intervention there has been great
success in preventing HIV from taking hold in needle stick patients.

Gary Stein
Brian Mailman - 04 Dec 2003 20:03 GMT
> > Someone may counsel you to agitate for a "DNA" test.  Don't.  It's my
> > understanding those are _too_ sensitive and can report a false
> > positive.  Diagnosis is not what they're designed for, it's like using a
> > pregnancy test to detect uterine cancer.

> Brian while PCR is indeed not labeled as a diagnostic test, it has become
> the standard of care in labs, and hospitals when dealing with one of there
> staff who has had a needle stick incident.

Do I misremember a long thread a couple years ago with Nick Bennett
talking to one of the (then) trolls on this subject?

B/
Poop Dogg - 04 Dec 2003 05:43 GMT
> About 3 weeks ago I had a brief unprotected sexual encounter (I am a
> male). There was approximately 5 seconds of unprotected
[quoted text clipped - 12 lines]
> an HIV
> test?

I think you need to wait several months before antibodies are detectable,
though the time may be less these days.  I remember when my brother
caught HIV.  He came down with a mysterious viral infection and felt
terrible and the doctor diagnosed it as mononucleosis.  Offhand, I would
say the symptoms appeared 1.5-2 weeks after exposure.  I believe swollen
lymph glands are an indication, though they also can indicate other
viral infections.

If you are really worried, go and demand a viral DNA test.  Don't let
them try to talk you out of it.  You will probably have to pay for it,
the cost is around $200 I think.  This test can detect even the tiniest
bit of HIV DNA, i.e. it can detect the virus within a day or so of
infection.  I believe blood banks recently adopted the test for the
screening of all blood donations because the previous antibody test
allowed for such a long period between infection and detection.
Curious - 04 Dec 2003 21:34 GMT
I have an appointment for a physical with a doctor on the 17th so I
can get some testing then. Or should I go sooner?

I had already been getting kind of sick leading up to my sexual
encounter. So I went to the doctor because I started running a really
bad fever a few days later and the doctor said it was Strep throat and
I got some antibiotics. They helped a lot and I was back to normal in
a few days pretty much. Other than that my lymph nodes have been fine
from what I can tell.

I spoke with the doctor about my sexual encounter and my concerns
since I did not know the woman at all nor would I be seeing her again
and the doctor said HIV/AIDS was not a concern of hers because of the
brevity of the contact/penetration (a few seconds and no ejaculation).
She was more concerned with other STDs. One of which I may have caught
because I am still having some issues with ejaculation which I think
is due to an infection. Have to go see a urologist about that one.

Thanks for reading my post and for putting up a response, it's nice to
just be able to talk about this. Been driving myself nuts keeping it
inside because I don't know if I'm making a big deal out of something
that isn't actually occurring in my body.

> I think you need to wait several months before antibodies are detectable,
> though the time may be less these days.  I remember when my brother
[quoted text clipped - 11 lines]
> screening of all blood donations because the previous antibody test
> allowed for such a long period between infection and detection.
LiL bItTy 01 - 08 Dec 2003 18:07 GMT
I'm a 37 year old female and we found out  my husband was HIV positive
10 months ago i tested then ,6 months after,and again last week i am not
positive could someone please tell me how that is posible?
Brian Mailman - 09 Dec 2003 03:23 GMT
> I'm a 37 year old female and we found out  my husband was HIV positive
> 10 months ago i tested then ,6 months after,and again last week i am not
> positive could someone please tell me how that is posible?

WOuldn't worry about the past, think about the future.

How can you keep from being infected?

B/
Poop Dogg - 09 Dec 2003 19:56 GMT
> I'm a 37 year old female and we found out  my husband was HIV positive
> 10 months ago i tested then ,6 months after,and again last week i am not
> positive could someone please tell me how that is posible?

Luck?  And don't forget that in the West heterosexual transmission
is uncommon, though certainly possible.  And about 1% or so of
Caucasians have a genetic mutation that causes an essential cell
receptor that HIV uses to latch on and infect to be deformed so
that the virus can't infect the cell.  You may be among one of
the lucky mutants!
D.Brown - 10 Dec 2003 19:29 GMT
>> I'm a 37 year old female and we found out  my husband was HIV positive
>> 10 months ago i tested then ,6 months after,and again last week i am not
[quoted text clipped - 6 lines]
>that the virus can't infect the cell.  You may be among one of
>the lucky mutants!

Thats quite a feat.. If HIV is an infectious agent, a virus mind you, your
saying that some Causcasians can actually prevent it from replicating, once
there infected ?..does the AMA know about this?  Is this ability recognized in
other infectious diseases?   Mmmmm Doubt it.

It is the greatest of all mistakes to do nothing because you can do only a
little. Do what you can.

~ Sydney Smith ~
Poop Dogg - 11 Dec 2003 02:22 GMT
"D.Brown" <D.Brown_member@newsguy.com> wrote...
> Thats quite a feat.. If HIV is an infectious agent, a virus mind you, your
> saying that some Causcasians can actually prevent it from replicating, once
> there infected ?..does the AMA know about this?  Is this ability recognized in
> other infectious diseases?   Mmmmm Doubt it.

It's true I tell you.  There are 2 cell receptors that HIV needs to
attach itself to in order to inject its DNA into the cell; CD4 and
CCR5 (and maybe one other).  I think it is the CCR5 receptor - some
people have a mutated version that prevents the HIV virus from
attaching to it and thereby preventing infection.  I'm sure there
are similar types of mutations in other types of cell receptors
that make people possessing them immune to viruses that use those
receptors to infect.  That is likely why flu and other contagious
disease epidemics don't infect everyone in the population - there
are always some survivors.  And conversely I suppose there are
cell receptor mutations that make people who possess them even more
susceptible to infection - perhaps that is why blacks always seem
to be more prone to HIV infection no matter where they are in the
world (even in the U.S. black HIV rates are far higher than white
rates).
D.Brown - 12 Dec 2003 19:48 GMT
>"D.Brown" <D.Brown_member@newsguy.com> wrote...
>> Thats quite a feat.. If HIV is an infectious agent, a virus mind you, your
[quoted text clipped - 7 lines]
>people have a mutated version that prevents the HIV virus from
>attaching to it and thereby preventing infection.

I thought CD4 was a tpye of White blood cell?  I thought  in order for a person
to develop AIDS there had to be a reduction of both CD4 and CD8 Cells?

 I'm sure there
>are similar types of mutations in other types of cell receptors
>that make people possessing them immune to viruses that use those
[quoted text clipped - 6 lines]
>world (even in the U.S. black HIV rates are far higher than white
>rates).

What you say maybe true, but in the case of African-Americans living in the U.S,
and in Africa, the progression of HIV into AIDS might have a more simplier
explaination than of a genetic mutation..Medical Mal-Misfeasence for one.

http://www.virusmyth.net/aids/data/mabcortico.htm

If HIV is such a killer virus, then you'd expect alot more people to be dying of
AIDS in in the U.S, What is your explaination for that? That White people are
genetically superior? Maybe those Protease Inhibitors work, eh?

It is the greatest of all mistakes to do nothing because you can do only a
little. Do what you can.

~ Sydney Smith ~
 
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