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Medical Forum / Diseases and Disorders / AIDS / February 2005

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anyone remember ribavirin?

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Brian Mailman - 20 Feb 2005 00:27 GMT
seems like it's good for something after all...

http://www.cnn.com/2005/WORLD/europe/02/19/germany.rabies.ap/index.html

b/
Bennett - 20 Feb 2005 16:04 GMT
> seems like it's good for something after all...

http://www.cnn.com/2005/WORLD/europe/02/19/germany.rabies.ap/index.html

> b/

It may yet make a comeback, with caveats, in RSV infection.  My boss
has some funky data which shows a hell of a difference if used in combo
with something else.

Can't give too much away - we're awaiting publication :-P

Bennett
Brian Mailman - 20 Feb 2005 17:47 GMT
>> seems like it's good for something after all...
>>
> http://www.cnn.com/2005/WORLD/europe/02/19/germany.rabies.ap/index.html

> It may yet make a comeback, with caveats, in RSV infection.

The Richard Nixon of anti-virals....

B/
Bennett - 21 Feb 2005 13:10 GMT
LOL :o)

It's an odd one.  I don't think anyone really knows how it works, and
it may well have different mechanisms for various viruses.

Still, the data we've got is pretty impressive - the trick is going to
be turning a mouse model into something clinically relevant.  Along
with the rest of the controls, Ribavarin alone doesn't do a whole lot.
There's a synergistic effect of sorts...

Bennett
Brian Mailman - 21 Feb 2005 17:53 GMT
> Still, the data we've got is pretty impressive - the trick is going to
> be turning a mouse model into something clinically relevant.

an understatement....

> Along with the rest of the controls, Ribavarin alone doesn't do a whole lot.
> There's a synergistic effect of sorts...

well cool... congrats on your persistence.

b/
 
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