LATEX PROCESSING CHEMICALS

http://www.itcilo.it/english/actrav/telearn/osh/ic/106490.htm

By John G. Downing, M..D.

First Published in the New England Journal of Medicine,

*    Highly Toxic or Irritant
*    Aniline
*    Hexamethyline-tetramine
*    Ortho-toluidine
*   
*    Slightly Toxic or Irritant
*    Alpha-naphthylamine
*    Beta Methyline aniline
*    Para-Phenylinediamine

FROM :-

http://193.51.164.11/htdocs/monographs/Suppl7/Toluidine-ortho.html

Overall evaluation: -

Ortho-Toluidine is possibly carcinogenic
to humans (Group 2B).

Para-toluidine

Inhalation Blue lips or finger nails. Blue skin. Confusion.
Dizziness. Headache. Laboured breathing. Nausea. Shortness of breath.
Unconsciousness. Weakness. Ingestion Blue lips or fingernails. Blue skin.

Dizziness. Headache. Laboured breathing (further see Inhalation).

ROUTES OF EXPOSURE:

The substance can be absorbed into the body by inhalation
and through the skin and by ingestion.

INHALATION RISK:

Evaporation at 20°C is negligible; a harmful concentration
of airborne particles can, however, be reached quickly on spraying or
when dispersed, especially if powdered.

EFFECTS OF SHORT-TERM EXPOSURE:

The substance irritates the eyes and the skin. The substance
may cause effects on the blood, bladder and kidneys , resulting in tissue

lesions and formation of methaemoglobin. Exposure to high concentrations
may result in damage to kidneys and bladder. The effects may be delayed.
Medical observation is indicated. See Notes.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:

Repeated or prolonged contact may cause skin sensitization.
The substance may have effects on the blood , resulting in formation of
methaemoglobin (see Notes). The following chemicals are known or suspected

carcinogens. This list has been compiled from a number of sources, but
it is not (and cannot be) comprehensive. Therefore, the absence of a
chemical
from this list does not mean that it cannot have carcinogenic properties.

Neither does the presence of a chemical in the list indicate that it is
a proven carcinogen. However, users should treat
the materials listed with the caution due to suspected carcinogens,
and gather as much safety data as possible before starting work.

Restrictions apply to the use of some of these chemicals
in the U.K. We have done our best to ensure the data below is as accurate

as possible, but cannot accept responsibility for its use or mis-use.

Aniline 4,4'-Methylenedianiline Trichlormethine (Trimustine
hydrochloride)

 

http://physchem.ox.ac.uk/MSDS/carcinogens.html
25249.8.

 

-o0o-

List Of Chemicals Known to Cause Cancer
Or Reproductive Toxicity.

(a) On or before March 1, 1987.

State of California

The Governor shall cause to be published a list of those
chemicals known to the state to cause cancer or
reproductive toxicity within the meaning of this chapter, and he
shall cause such list to be revised and republished in light of additional

knowledge at least once per year thereafter. Such list shall include at
a minimum those substances identified by reference in Labor Code Section
6382(b)(1) and those substances identified additionally by reference in
Labor Code Section 6382(d).

*    Aniline 62533 January 1, 1990

*    Benzene 71432 February 27, 1987

*    Trichlormethine (Trimustine hydrochloride)
817094 January 1, 1992
*    4,4'-Methylenedianiline 101779
January 1, 1988
*    4,4'-Methylenedianiline dihydrochloride
13552448 January 1, 1988

FROM CANCER DATABASE

benzene, aromatic amines – Rubber processing chemicals

Carcinogen

http://www.bccancer.bc.ca/cid/25-3.html