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Medical Forum / Diseases and Disorders / AIDS / January 2005

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AMERICAN CANCER SOCIETY ON CONDOM CANCER

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PaulKing - 05 Jan 2005 02:42 GMT
AMERICAN CANCER SOCIETY

http://www.cancer.org/docroot/CRI/content/CRI_2_6x_Talcum_Powder_and_Cancer.asp?
sitearea
=

    
Talcum Powder and Cancer
Talcum powder is produced from talc, a magnesium trisilicate mineral,
which in its natural form may contain asbestos, a known human carcinogen.
Because of this association with asbestos, all home-use talcum products
marketed after about 1973 - baby powders, body powders, facial powders -
have been required by law to be asbestos-free. Asbestos can cause lung
cancer and mesotheliomas (cancers affecting the lining surfaces of the
pleural and peritoneal cavities).

It has been suggested that talcum powder may be carcinogenic to the
covering layer of the ovaries through the migration of talcum powder
particles (applied to the genital area, sanitary napkins, diaphragms, or
condoms) through the vagina, uterus, and fallopian tubes to the ovary.
Several epidemiologic studies have examined the relationship between
talcum powder and cancer of the ovary. Findings are mixed, with some
studies reporting a slightly increased risk and some reporting no
association. A case-control study published in 1997 of 313 women with
ovarian cancer and 422 without this disease found that the women with
cancer were more likely to have applied talcum powder to their external
genital area or to have used genital deodorant sprays. Women using these
products had a 50% to 90% higher risk of developing ovarian cancer.
Storing diaphragms with powder did not significantly increase cancer
risk.
Since many of these women might have used products with more asbestos
contamination than that in current products, the ovarian cancer risk for
current users is difficult to evaluate. Until additional information is
available, women may wish to consider avoiding these products or
substituting cornstarch-based powders that contain no talc. One study has
suggested that an increased risk, if it exists, might be confined to
borderline and endometrioid (uterine-like) tumors and therefore might not
affect the majority of ovarian cancers. Experimental toxicology studies
have suggested carcinogenicity of inhaled, asbestos-free talc powder in
some rodent species but not in others. The most recent publication on
this
topic, a prospective study (considered to generally be the most
informative) found no effect on ovarian cancer overall but a 40% increase
risk in one type -- invasive serous cancers.

No increased risk of human lung cancer has been reported in association
with the use of cosmetic talcum powder. Although some studies of talc
miners and millers have suggested an increased risk of lung cancer and
other respiratory diseases, the industrial grade talc to which such
workers are exposed contains varying amounts of silica and asbestos,
unlike the purified talc sold to consumers. One study of pottery workers
exposed to silica dust and nonasbestiform talc showed an excess risk of
lung cancer, while other studies of occupational talc exposure have not
found an increased risk. While experimental evidence suggests that some
forms of silica may cause cancer in animals, observational studies in
humans are not conclusive.

REFERENCES

Cook LS, Kamb ML, Weiss NS. Perineal powder exposure and the risk of
ovarian cancer. Am J Epidemiol 1997; 145:459-465.

Gertrg DM, Hunter DJ, Cramer DW, Colditz GA, Speizer FE, Willett WC,
Hankinson SE. Prospective study of talc use and ovarian cancer. J Natl
Cancer Inst; 2000: 92:249-252.

Harlow BL, Cramer DW, Bell DA, Welch WR. Perineal exposure to talc and
ovarian cancer risk. Obstet Gynecol 1992; 80: 19-26.

Hartge P, Stewart PA. Occupation and ovarian cancer: a case-control study
in the Washington DC metropolitan area, 1978-1981. J Occup Med 1994; 36
(8): 924-927.

Thomas TL, Stewart PA. Mortality from lung cancer and respiratory disease
among pottery workers exposed to silica and talc. Am J Epidemiol 1987;
125
(1): 35-43.

Revised: 02/03/2000
GMCarter - 05 Jan 2005 10:43 GMT
>AMERICAN CANCER SOCIETY
>
>http://www.cancer.org/docroot/CRI/content/CRI_2_6x_Talcum_Powder_and_Cancer.asp?
sitearea
=
>
>    
>Talcum Powder and Cancer

Talcum powder is not the same as condoms.

Oh--but if 7000=0, then talcum=condoms probably works in your
mysterious, psychedelic world....
PaulKing - 05 Jan 2005 22:51 GMT
Talc powder is used on almost all condoms to stop the latex sticking
together after dipping.

See the other articles which clearly state this.

You are an idiot and/or a lier.

BOTH!
GMCarter - 05 Jan 2005 23:04 GMT
>Talc powder is used on almost all condoms to stop the latex sticking
>together after dipping.
>
>See the other articles which clearly state this.

LOL. Articles YOU posted? I reject your assertions because you lie
like a rug!

>You are an idiot and/or a lier.
>
>BOTH!

In the immortal words of that evil creep Cheney, "go f.ck yourself."
You won't need a condom then.
PaulKing - 05 Jan 2005 22:52 GMT
Authors: Kasper, Candace Sue; Chandler, P.J., Jr.
Citation: JAMA, The Journal of the American Medical Association, March
15,
1995 v273 n11 p846(2)

This risk is due to tale, a dry lubricant present on the surface of
condoms. Talc is a known sclerosing agent, which if introduced into the
female reproductive tract may result in fallopian tube fibrosis with
resultant infertility.[1] Of even greater concern are studies linking
talc
to ovarian cancer.[2-4]

Our interest in tale arose fortuitously during a clinico-pathologic study
of fibrotic capsules surrounding silicone gel-filled breast implants. We
found talc, an unwanted contaminant, within 70% of the capsules
evaluated.[5] Microscopic examination of powder on the surface of
archived
surgical gloves revealed that gloves manufactured before 1991 probably
represented the source of tale found in implant cavities (unpublished
data, Plastic Surgery Research Forum, April 1994). We also examined other
health- and consumer-related latex devices and determined that condoms
and
dental dams were coated with varying amounts of talc, but that pacifiers
and baby bottle nipples were talc free (Table).

The harmful effect of talc on human tissue was first recognized in the
1930s when postoperative granulomatous peritonitis and fibrous adhesions
were causally linked to surgical glove-donning powders. Thirty years
later, Saxen et al[1] reported foreign-body granulomatous peritonitis in
a
woman with no previous history of abdominal surgery. Particulate matter
found within her peritoneal granulomas was identical to material found on
the surface of condoms used by her husband. The authors concluded that
material in the condom lubricant traveled upward through the fallopian
tubes and became implanted within the patient's peritoneal cavity; they
also predicted that condom lubricants might contribute to tubal occlusion
and sterility.

A more ominous series of studies linked talc to ovarian carcinoma; talc
was observed in a number of ovarian and uterine tumors as well as in
normal ovarian tissue.[1,3] It was hypothesized that deodorizing tales
placed on the perineum (or on the surface of condoms and diaphragms)
reached the ovaries via ascent through the fallopian tubes.[24] In
support
of this hypothesis, retrospective analyses demonstrated that women who
used deodorizing powders on sanitary napkins, but who had blocked tubes
and/or hysterectomies, had a lesser incidence of ovarian carcinoma than
women with patent tubes.[2]

Although tale is no longer used as a surgical glove-donning powder, it is
still used as a surface lubricant on the majority of condoms manufactured
in the United States and abroad. Remarkably, the Food and Drug
Administration never addressed the issue of talc on the surface of
condoms, even though they required surgical glove manufacturers to remove
all tales used in processing.

The last 10 years has seen a dramatic increase in the use of condoms. If
tale contributes to ovarian carcinoma and/or fallopian tube sclerosis, we
predict a significant increase in the incidence of ovarian carcinoma and
infertility due to the deleterious effects of condom talc. We do not
advocate abandoning condom use. To obviate the risk of talc-associated
morbidity in sexually active women, we strongly urge condom distributors
to eliminate all tales used in condom manufacture.

[1.] Saxen L, Kassinen A, Saxen E. Peritoneal foreign-body reaction
caused
by condom emulsion. Lancet. 1963;1:1295-1296. [2.] Longo D, Young

R. Cosmetic tale and ovarian cancer. Lancet. 1979;2:349-351. [3.]
Henderson W, Joslin C, Turnbull A, Griffiths K. Tale and carcinoma of the
ovary and cervix. J Obstet Gynecol Br Commonwealth. 1971;78:266-272. [4.]
Harlow B, Weiss N. A case-control study of borderline ovarian tumors: the
influence of perineal exposure to tale. Am J Epidemiol. 1989;130.390-M.
[5.] Kasper C, Chandler P. Talc deposition in skin and tissues
surrounding
silicone gel-containing prosthetic devices. Arch Dermatol.
1994-130:48-53.

http://womnhlth.home.mindspring.com/studies/possibo2.html
GMCarter - 05 Jan 2005 23:24 GMT
>Authors: Kasper, Candace Sue; Chandler, P.J., Jr.
>Citation: JAMA, The Journal of the American Medical Association, March
>15,
>1995 v273 n11 p846(2)

Written in 1995. See now:
http://www.stopaids.org/resources/free_condoms/condom_types.html

and

http://www.kaisernetwork.org/daily_reports/rep_index.cfm?DR_ID=27482

and

http://www.consumerreports.org/main/content/display_report.jsp?WebLogicSession=Q
dv21LPEXbIOzaTPr3CjAXoNA7mzRSuKNNambjrQJa86jDPjqPTD|-7713857185340821589/1699379
09/6/7005/7005/7002/7002/7005/-1|-7976650973904308052/169937904/6/7005/7005/7002
/7002/7005/-1&FOLDER%3C%3Efolder_id=551087&ASSORTMENT%3C%3East_id=333141&bmUID=1
104934613044


and
http://www.consumerreports.org/main/content/display_report.jsp?WebLogicSession=Q
dxzYoOGAMtyU9WWk1s2X8HcNHnsd0mOyz9ekCJnXh4dpAFcFHe6|-7713857185340821589/1699379
09/6/7005/7005/7002/7002/7005/-1|-7976650973904308052/169937904/6/7005/7005/7002
/7002/7005/-1&FOLDER%3C%3Efolder_id=551083&ASSORTMENT%3C%3East_id=333141&bmUID=1
104966499128


see also:
http://www.protectingourhealth.org/newscience/ovariancancer/2004-0217peerreviewo
varian.htm


Yes, ovarian cancer is a serious problem. Happily, pretty rare. Given
the risks of sex without a condom for many people, the talc issue is
controversial. Indeed, whether simply using a condom that MIGHT have
talc on it during sex is sufficient to increase a risk for ovarian
cancer is not necessarily support (whereas use of talcum powder in the
gential area would provide a higher concentration). See below for an
excerpt from the last URL of the list above.

Indeed, one study (abstract below) that provided some evidence for a
role of talc in ovarian cancer also suggested that condom use was not
likely to be relevant.

Cramer DW, Welch WR, Scully RE, Wojciechowski CA. Ovarian cancer and
talc: a case-control study. Cancer. 1982 Jul 15;50(2):372-376.

Opportunities for genital exposure to talc were assessed in 215 white
females with epithelial ovarian cancers and in 215 control women from
the general population matched by age, race, and residence. Ninety-two
(42.8%) cases regularly used talc either as a dusting powder on the
perineum or on sanitary napkins compared with 61 (28.4%) controls.
Adjusted for parity and menopausal status, this difference yielded a
relative risk of 1.92 (P less than 0.003) for ovarian cancer
associated with these practices. Women who had regularly engaged in
both practices had an adjusted relative risk of 3.28 (P less than
0.001) compared to women with neither exposure. This provides some
support for an association between talc and ovarian cancer
hypothesized because of the similarity of ovarian cancer to
mesotheliomas and the chemical relation of talc to asbestos, a known
cause of mesotheliomas. The authors also investigated opportunities
for potential talc exposure from rubber products such as condoms or
diaphragms or from pelvic surgery. No significant differences were
noted between cases and controls in these exposures, although the

In any event, some condoms have replaced talc with corn starch. For
example:
http://www.1clickcondoms.com/Condoms/Lifestyles/67/Lifestyles-Large.html

Frankly, I'd be more concerned with condoms that have nonoxynol-9 as a
lubricant and would avoid those.

So once again, Paul, you'll probably post this same study over and
over and over despite the fact the evidence is pretty weak for the
hysterical, squealing raging claims you make that somehow you twist
around in your little pea brain to justify f.cking without a condom.

        George M. Carter

**
Talc and Ovarian Cancer

The potential association between use of talc powders in the genital
area and development of ovarian cancer is extremely controversial.
Talcum powder may be applied directly to the genital area after
bathing, or may be sprinkled on sanitary napkins. In addition, talc
may be used on condoms or on diaphragms. One experimental study found
that carbon particles deposited in the vagina can travel up into the
fallopian tubes within 30 minutes, implying that talc applied to the
genital area may also do so (Egli and Newton 1961). A pathology study
done in the early 1970’s found embedded talc particles in 75% of
ovarian tumors sampled (Henderson et al. 1971). Talc has been
suspected for many years because it is chemically related to asbestos,
and because talcum powders in the past were contaminated with asbestos
fibers. Women occupationally exposed to asbestos have been reported to
have an increased risk of ovarian cancer (Keal 1960). In addition, one
of the most common types of ovarian cancer, invasive serous cancers,
very closely resemble mesotheliomas. Mesothelioma is a type of cancer
that is specifically associated with exposure to asbestos. On the
other side of the debate, several studies in which talc was injected
directly into the ovaries of rats failed to identify significant
increases in ovarian cancer (Wehner 2002).

Several retrospective studies comparing women with ovarian cancer and
similar women without the disease, have reported apparent associations
between talc usage and ovarian cancer. Some of these studies have
reported only marginal associations, whereas others have reported
risks up to nearly 2.5-fold (Chang and Risch 1997). Twelve fairly
large case-control studies reported associations between talc exposure
and ovarian cancer, whereas three small studies did not find any
association. One study of more than a thousand women found that 45% of
women with ovarian cancer reported using talc in their genital area,
compared to 36% of women without the disease, leading to an overall
increased relative risk of about 60%. Women who did not themselves use
the powder, but whose husbands regularly used talc on their genitals
also had a 50% increased risk of ovarian cancer. The only women in
this study who failed to show such an association were those who had
previously had a tubal ligation, implying that closing off the pathway
from the external genitals to the ovaries may be protective (Cramer et
al. 1999). In addition, use of talc prior to pregnancy was associated
with a much higher risk than talc usage after pregnancy, implying that
changes may occur in the ovary during pregnancy that may decrease
susceptibility. The authors of this study predicted that approximately
10% of ovarian cancer cases in the general population may be
attributable to talc usage.

The increasingly persuasive body of research on talc and ovarian
cancer was called into question in February of 2000, when a
prospective study was published looking at this issue as part of the
very large Nurses’ Health Study (Gertig et al. 2000). Among the over
78,000 women in the cohort for analysis, 307 women were diagnosed with
ovarian cancer by June of 1996. Previously, in 1982, all the women had
answered questions about talc use in the genital area. The question
was phrased to ascertain whether they had ‘ever’ used talc, making it
difficult to ascertain when the usage occurred or whether it was
ongoing. In this study, there was no overall association between use
of talc and ovarian cancer, even when the researchers attempted to
take into consideration numerous factors that could affect the
association. However, there was approximately a 40% greater report of
ever using talc among those women who later developed serous invasive
ovarian cancers. The serous cell type accounts for more than half of
all invasive ovarian cancers, has been linked to asbestos, and was
previously associated with talc in another study.

A combined analysis of sixteen studies on talc and ovarian cancer
included a total of 11,933 women (Huncharek et al. 2003). The pooled
results of this analysis showed an overall 33 percent increased risk
of ovarian cancer with talc use, which was statistically significant.
However, the authors of the analysis nonetheless questioned the
validity of this result for two reasons: first, there was no clear
dose-response relationship where women who reported more or longer use
of talc were at higher risk, and second, the studies that used
comparison patients who were hospitalized with other diseases did not
find any difference in talc usage, and only the studies that used
healthy women for comparison found an association. The authors
believed that this could mean that flaws in study design might explain
the apparent association.
PaulKing - 05 Jan 2005 22:51 GMT
  Talc

This is found in baby powders, face powders, body powders as well as some
contraceptives such as condoms.  Talc is a known carcinogen and is a
major
cause of ovarian cancer when used in the genital area.  It can be harmful
if inhaled as it can lodge in the lungs, causing respiratory disorders.

http://www.anewlife.co.uk/toxic-toiletries.html
 
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