Medical Forum / Diseases and Disorders / AIDS / January 2005
AMERICAN CANCER SOCIETY ON CONDOM CANCER
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PaulKing - 05 Jan 2005 02:42 GMT AMERICAN CANCER SOCIETY
http://www.cancer.org/docroot/CRI/content/CRI_2_6x_Talcum_Powder_and_Cancer.asp? sitearea=
Talcum Powder and Cancer Talcum powder is produced from talc, a magnesium trisilicate mineral, which in its natural form may contain asbestos, a known human carcinogen. Because of this association with asbestos, all home-use talcum products marketed after about 1973 - baby powders, body powders, facial powders - have been required by law to be asbestos-free. Asbestos can cause lung cancer and mesotheliomas (cancers affecting the lining surfaces of the pleural and peritoneal cavities).
It has been suggested that talcum powder may be carcinogenic to the covering layer of the ovaries through the migration of talcum powder particles (applied to the genital area, sanitary napkins, diaphragms, or condoms) through the vagina, uterus, and fallopian tubes to the ovary. Several epidemiologic studies have examined the relationship between talcum powder and cancer of the ovary. Findings are mixed, with some studies reporting a slightly increased risk and some reporting no association. A case-control study published in 1997 of 313 women with ovarian cancer and 422 without this disease found that the women with cancer were more likely to have applied talcum powder to their external genital area or to have used genital deodorant sprays. Women using these products had a 50% to 90% higher risk of developing ovarian cancer. Storing diaphragms with powder did not significantly increase cancer risk. Since many of these women might have used products with more asbestos contamination than that in current products, the ovarian cancer risk for current users is difficult to evaluate. Until additional information is available, women may wish to consider avoiding these products or substituting cornstarch-based powders that contain no talc. One study has suggested that an increased risk, if it exists, might be confined to borderline and endometrioid (uterine-like) tumors and therefore might not affect the majority of ovarian cancers. Experimental toxicology studies have suggested carcinogenicity of inhaled, asbestos-free talc powder in some rodent species but not in others. The most recent publication on this topic, a prospective study (considered to generally be the most informative) found no effect on ovarian cancer overall but a 40% increase risk in one type -- invasive serous cancers.
No increased risk of human lung cancer has been reported in association with the use of cosmetic talcum powder. Although some studies of talc miners and millers have suggested an increased risk of lung cancer and other respiratory diseases, the industrial grade talc to which such workers are exposed contains varying amounts of silica and asbestos, unlike the purified talc sold to consumers. One study of pottery workers exposed to silica dust and nonasbestiform talc showed an excess risk of lung cancer, while other studies of occupational talc exposure have not found an increased risk. While experimental evidence suggests that some forms of silica may cause cancer in animals, observational studies in humans are not conclusive.
REFERENCES
Cook LS, Kamb ML, Weiss NS. Perineal powder exposure and the risk of ovarian cancer. Am J Epidemiol 1997; 145:459-465.
Gertrg DM, Hunter DJ, Cramer DW, Colditz GA, Speizer FE, Willett WC, Hankinson SE. Prospective study of talc use and ovarian cancer. J Natl Cancer Inst; 2000: 92:249-252.
Harlow BL, Cramer DW, Bell DA, Welch WR. Perineal exposure to talc and ovarian cancer risk. Obstet Gynecol 1992; 80: 19-26.
Hartge P, Stewart PA. Occupation and ovarian cancer: a case-control study in the Washington DC metropolitan area, 1978-1981. J Occup Med 1994; 36 (8): 924-927.
Thomas TL, Stewart PA. Mortality from lung cancer and respiratory disease among pottery workers exposed to silica and talc. Am J Epidemiol 1987; 125 (1): 35-43.
Revised: 02/03/2000
GMCarter - 05 Jan 2005 10:43 GMT >AMERICAN CANCER SOCIETY > >http://www.cancer.org/docroot/CRI/content/CRI_2_6x_Talcum_Powder_and_Cancer.asp? sitearea= > > >Talcum Powder and Cancer Talcum powder is not the same as condoms.
Oh--but if 7000=0, then talcum=condoms probably works in your mysterious, psychedelic world....
PaulKing - 05 Jan 2005 22:51 GMT Talc powder is used on almost all condoms to stop the latex sticking together after dipping.
See the other articles which clearly state this.
You are an idiot and/or a lier.
BOTH!
GMCarter - 05 Jan 2005 23:04 GMT >Talc powder is used on almost all condoms to stop the latex sticking >together after dipping. > >See the other articles which clearly state this. LOL. Articles YOU posted? I reject your assertions because you lie like a rug!
>You are an idiot and/or a lier. > >BOTH! In the immortal words of that evil creep Cheney, "go f.ck yourself." You won't need a condom then.
PaulKing - 05 Jan 2005 22:52 GMT Authors: Kasper, Candace Sue; Chandler, P.J., Jr. Citation: JAMA, The Journal of the American Medical Association, March 15, 1995 v273 n11 p846(2)
This risk is due to tale, a dry lubricant present on the surface of condoms. Talc is a known sclerosing agent, which if introduced into the female reproductive tract may result in fallopian tube fibrosis with resultant infertility.[1] Of even greater concern are studies linking talc to ovarian cancer.[2-4]
Our interest in tale arose fortuitously during a clinico-pathologic study of fibrotic capsules surrounding silicone gel-filled breast implants. We found talc, an unwanted contaminant, within 70% of the capsules evaluated.[5] Microscopic examination of powder on the surface of archived surgical gloves revealed that gloves manufactured before 1991 probably represented the source of tale found in implant cavities (unpublished data, Plastic Surgery Research Forum, April 1994). We also examined other health- and consumer-related latex devices and determined that condoms and dental dams were coated with varying amounts of talc, but that pacifiers and baby bottle nipples were talc free (Table).
The harmful effect of talc on human tissue was first recognized in the 1930s when postoperative granulomatous peritonitis and fibrous adhesions were causally linked to surgical glove-donning powders. Thirty years later, Saxen et al[1] reported foreign-body granulomatous peritonitis in a woman with no previous history of abdominal surgery. Particulate matter found within her peritoneal granulomas was identical to material found on the surface of condoms used by her husband. The authors concluded that material in the condom lubricant traveled upward through the fallopian tubes and became implanted within the patient's peritoneal cavity; they also predicted that condom lubricants might contribute to tubal occlusion and sterility.
A more ominous series of studies linked talc to ovarian carcinoma; talc was observed in a number of ovarian and uterine tumors as well as in normal ovarian tissue.[1,3] It was hypothesized that deodorizing tales placed on the perineum (or on the surface of condoms and diaphragms) reached the ovaries via ascent through the fallopian tubes.[24] In support of this hypothesis, retrospective analyses demonstrated that women who used deodorizing powders on sanitary napkins, but who had blocked tubes and/or hysterectomies, had a lesser incidence of ovarian carcinoma than women with patent tubes.[2]
Although tale is no longer used as a surgical glove-donning powder, it is still used as a surface lubricant on the majority of condoms manufactured in the United States and abroad. Remarkably, the Food and Drug Administration never addressed the issue of talc on the surface of condoms, even though they required surgical glove manufacturers to remove all tales used in processing.
The last 10 years has seen a dramatic increase in the use of condoms. If tale contributes to ovarian carcinoma and/or fallopian tube sclerosis, we predict a significant increase in the incidence of ovarian carcinoma and infertility due to the deleterious effects of condom talc. We do not advocate abandoning condom use. To obviate the risk of talc-associated morbidity in sexually active women, we strongly urge condom distributors to eliminate all tales used in condom manufacture.
[1.] Saxen L, Kassinen A, Saxen E. Peritoneal foreign-body reaction caused by condom emulsion. Lancet. 1963;1:1295-1296. [2.] Longo D, Young
R. Cosmetic tale and ovarian cancer. Lancet. 1979;2:349-351. [3.] Henderson W, Joslin C, Turnbull A, Griffiths K. Tale and carcinoma of the ovary and cervix. J Obstet Gynecol Br Commonwealth. 1971;78:266-272. [4.] Harlow B, Weiss N. A case-control study of borderline ovarian tumors: the influence of perineal exposure to tale. Am J Epidemiol. 1989;130.390-M. [5.] Kasper C, Chandler P. Talc deposition in skin and tissues surrounding silicone gel-containing prosthetic devices. Arch Dermatol. 1994-130:48-53.
http://womnhlth.home.mindspring.com/studies/possibo2.html
GMCarter - 05 Jan 2005 23:24 GMT >Authors: Kasper, Candace Sue; Chandler, P.J., Jr. >Citation: JAMA, The Journal of the American Medical Association, March >15, >1995 v273 n11 p846(2) Written in 1995. See now: http://www.stopaids.org/resources/free_condoms/condom_types.html
and
http://www.kaisernetwork.org/daily_reports/rep_index.cfm?DR_ID=27482
and
http://www.consumerreports.org/main/content/display_report.jsp?WebLogicSession=Q dv21LPEXbIOzaTPr3CjAXoNA7mzRSuKNNambjrQJa86jDPjqPTD|-7713857185340821589/1699379 09/6/7005/7005/7002/7002/7005/-1|-7976650973904308052/169937904/6/7005/7005/7002 /7002/7005/-1&FOLDER%3C%3Efolder_id=551087&ASSORTMENT%3C%3East_id=333141&bmUID=1 104934613044
and http://www.consumerreports.org/main/content/display_report.jsp?WebLogicSession=Q dxzYoOGAMtyU9WWk1s2X8HcNHnsd0mOyz9ekCJnXh4dpAFcFHe6|-7713857185340821589/1699379 09/6/7005/7005/7002/7002/7005/-1|-7976650973904308052/169937904/6/7005/7005/7002 /7002/7005/-1&FOLDER%3C%3Efolder_id=551083&ASSORTMENT%3C%3East_id=333141&bmUID=1 104966499128
see also: http://www.protectingourhealth.org/newscience/ovariancancer/2004-0217peerreviewo varian.htm
Yes, ovarian cancer is a serious problem. Happily, pretty rare. Given the risks of sex without a condom for many people, the talc issue is controversial. Indeed, whether simply using a condom that MIGHT have talc on it during sex is sufficient to increase a risk for ovarian cancer is not necessarily support (whereas use of talcum powder in the gential area would provide a higher concentration). See below for an excerpt from the last URL of the list above.
Indeed, one study (abstract below) that provided some evidence for a role of talc in ovarian cancer also suggested that condom use was not likely to be relevant.
Cramer DW, Welch WR, Scully RE, Wojciechowski CA. Ovarian cancer and talc: a case-control study. Cancer. 1982 Jul 15;50(2):372-376.
Opportunities for genital exposure to talc were assessed in 215 white females with epithelial ovarian cancers and in 215 control women from the general population matched by age, race, and residence. Ninety-two (42.8%) cases regularly used talc either as a dusting powder on the perineum or on sanitary napkins compared with 61 (28.4%) controls. Adjusted for parity and menopausal status, this difference yielded a relative risk of 1.92 (P less than 0.003) for ovarian cancer associated with these practices. Women who had regularly engaged in both practices had an adjusted relative risk of 3.28 (P less than 0.001) compared to women with neither exposure. This provides some support for an association between talc and ovarian cancer hypothesized because of the similarity of ovarian cancer to mesotheliomas and the chemical relation of talc to asbestos, a known cause of mesotheliomas. The authors also investigated opportunities for potential talc exposure from rubber products such as condoms or diaphragms or from pelvic surgery. No significant differences were noted between cases and controls in these exposures, although the
In any event, some condoms have replaced talc with corn starch. For example: http://www.1clickcondoms.com/Condoms/Lifestyles/67/Lifestyles-Large.html
Frankly, I'd be more concerned with condoms that have nonoxynol-9 as a lubricant and would avoid those.
So once again, Paul, you'll probably post this same study over and over and over despite the fact the evidence is pretty weak for the hysterical, squealing raging claims you make that somehow you twist around in your little pea brain to justify f.cking without a condom.
George M. Carter
** Talc and Ovarian Cancer
The potential association between use of talc powders in the genital area and development of ovarian cancer is extremely controversial. Talcum powder may be applied directly to the genital area after bathing, or may be sprinkled on sanitary napkins. In addition, talc may be used on condoms or on diaphragms. One experimental study found that carbon particles deposited in the vagina can travel up into the fallopian tubes within 30 minutes, implying that talc applied to the genital area may also do so (Egli and Newton 1961). A pathology study done in the early 1970s found embedded talc particles in 75% of ovarian tumors sampled (Henderson et al. 1971). Talc has been suspected for many years because it is chemically related to asbestos, and because talcum powders in the past were contaminated with asbestos fibers. Women occupationally exposed to asbestos have been reported to have an increased risk of ovarian cancer (Keal 1960). In addition, one of the most common types of ovarian cancer, invasive serous cancers, very closely resemble mesotheliomas. Mesothelioma is a type of cancer that is specifically associated with exposure to asbestos. On the other side of the debate, several studies in which talc was injected directly into the ovaries of rats failed to identify significant increases in ovarian cancer (Wehner 2002).
Several retrospective studies comparing women with ovarian cancer and similar women without the disease, have reported apparent associations between talc usage and ovarian cancer. Some of these studies have reported only marginal associations, whereas others have reported risks up to nearly 2.5-fold (Chang and Risch 1997). Twelve fairly large case-control studies reported associations between talc exposure and ovarian cancer, whereas three small studies did not find any association. One study of more than a thousand women found that 45% of women with ovarian cancer reported using talc in their genital area, compared to 36% of women without the disease, leading to an overall increased relative risk of about 60%. Women who did not themselves use the powder, but whose husbands regularly used talc on their genitals also had a 50% increased risk of ovarian cancer. The only women in this study who failed to show such an association were those who had previously had a tubal ligation, implying that closing off the pathway from the external genitals to the ovaries may be protective (Cramer et al. 1999). In addition, use of talc prior to pregnancy was associated with a much higher risk than talc usage after pregnancy, implying that changes may occur in the ovary during pregnancy that may decrease susceptibility. The authors of this study predicted that approximately 10% of ovarian cancer cases in the general population may be attributable to talc usage.
The increasingly persuasive body of research on talc and ovarian cancer was called into question in February of 2000, when a prospective study was published looking at this issue as part of the very large Nurses Health Study (Gertig et al. 2000). Among the over 78,000 women in the cohort for analysis, 307 women were diagnosed with ovarian cancer by June of 1996. Previously, in 1982, all the women had answered questions about talc use in the genital area. The question was phrased to ascertain whether they had ever used talc, making it difficult to ascertain when the usage occurred or whether it was ongoing. In this study, there was no overall association between use of talc and ovarian cancer, even when the researchers attempted to take into consideration numerous factors that could affect the association. However, there was approximately a 40% greater report of ever using talc among those women who later developed serous invasive ovarian cancers. The serous cell type accounts for more than half of all invasive ovarian cancers, has been linked to asbestos, and was previously associated with talc in another study.
A combined analysis of sixteen studies on talc and ovarian cancer included a total of 11,933 women (Huncharek et al. 2003). The pooled results of this analysis showed an overall 33 percent increased risk of ovarian cancer with talc use, which was statistically significant. However, the authors of the analysis nonetheless questioned the validity of this result for two reasons: first, there was no clear dose-response relationship where women who reported more or longer use of talc were at higher risk, and second, the studies that used comparison patients who were hospitalized with other diseases did not find any difference in talc usage, and only the studies that used healthy women for comparison found an association. The authors believed that this could mean that flaws in study design might explain the apparent association.
PaulKing - 05 Jan 2005 22:51 GMT Talc
This is found in baby powders, face powders, body powders as well as some contraceptives such as condoms. Talc is a known carcinogen and is a major cause of ovarian cancer when used in the genital area. It can be harmful if inhaled as it can lodge in the lungs, causing respiratory disorders.
http://www.anewlife.co.uk/toxic-toiletries.html
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