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Medical Forum / Diseases and Disorders / AIDS / December 2004Great odds?
Side Effects Reported Incidence Rates* PROTEASE INHIBITORS Saquinavir (Invirase or Fortovase) Diarrhea 15-20% Vomiting 3-5% Nausea 10-15% Acid reflux 9% Headaches 5-9% Fatigue 5-9% Elevated liver enzymes 2-6% Ritonavir (Norvir) Weakness 9-28% Abdominal pain 4-7% Decreased appetite 6-8% Nausea 23-47% Diarrhea 18-22% Vomiting 15-22% Paresthesia (mouth tingling or numbness) 5-6% Altered taste sensations 5-16% Elevated liver enzymes 3-15% Elevated creatinine (measure of kidney function) 7-9% Indinavir (Crixivan) Kidney stone or sludge/flank pain 4-37% Elevated liver enzymes 10-12% Abdominal pain 9% Nausea 2-7% Nelfinavir (Viracept) Diarrhea 20-32% Nausea 2-7% Amprenavir (Agenerase) Diarrhea 51% Nausea 37% Vomiting 23% Headache 24% Rash 28% Paresthesia 25% Fatigue 23% Side Effects Reported Incidence Rates* NUCLEOSIDE ANALOGS AZT (Retrovir)** Anemia 1-29% Granulocytopenia (shortage of a type of white blood cell) 2-37% Abdominal pain 9% Decreased appetite 20% Constipation 6% Dizziness 6% Headache 18% Muscle Pain 62% Nausea 51% Vomiting 17% 3TC (Epivir) Diarrhea 18% Nausea 3% Dizziness 10% Decreased appetite 10% Depression 9% Insomnia 11% Nasal problems 20% Headache 35% d4T (Zerit) Peripheral neuropathy 13-24% Pancreatitis 7-13% Abdominal pain 34% Nausea and vomiting 38% Diarrhea 50% Headache 54% Rash 40% Insomnia 29% Decreased appetite 19% Elevated liver enzymes 11-13% Neutropenia (shortage of a type of white blood cell) 5% Elevated amylase levels (indicator of possible pancreatitis 14% ddC (Hivid) Peripheral neuropathy 22-35% ddI (Videx) Peripheral neropathy 16-34% Pancreatitis 7-13% Diarrhea 16-34% Abacavir (Ziagen) Nausea 47% Diarrhea 12% Decreased appetite 11% Insomnia 7% Hypersensitivity reaction 3-5% Side Effects Reported Incidence Rates* NUCLEOTIDE ANALOG Adefovir (Preveon) Renal (kidney) toxicities 17-32% NNRTIs (NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS) Nevirapine (Viramune) Rash 24-37% Delavirdine (Rescriptor) Rash 18% Neutropenia 3-7% Elevated amylase levels 1-7% Efavirenz (Sustiva) Central nervous system problems (headache, insomnia, dizziness, malaise, anxiety 25-40% Rash 12% Nausea 10-20% * Only side effects reported by at least 5 percent of the drug's users are included. ** Some percentages listed here date from AZT's earliest use, with a much higher dosage than is now recommended POZ May 1999 Excellent post, Paul. One must keep in mind that the longer one takes a drug, the liklier it is that one will experience some or most of the "side effects" (quotations are important as these are NOT merely side effects, but rather are the DIRECT effects of these nasty immune killing drugs). Blackie >Side Effects Reported Incidence Rates* >PROTEASE INHIBITORS [quoted text clipped - 103 lines] >higher dosage than is now recommended >POZ May 1999 http://www.ardice.com/Health/Pharmacy/Drugs_and_Medications/A/Adefovir/ Two HIV drug ads misleading, says FDA Promotions for Kaletra omit life-threatening safety risks Updated: 7:33 p.m. ET Nov. 2, 2004 WASHINGTON - Two Abbott Laboratories Inc. promotions for HIV-fighting drug Kaletra exaggerated benefits and left out information about life-threatening safety risks, U.S. regulators charged in a letter made public Tuesday. The Food and Drug Administration ordered the company to stop circulating the advertisements immediately. One ran in POZ, a magazine aimed at people with the HIV virus, and another was posted in restrooms, the FDA said. “These promotional pieces overstate the effectiveness of Kaletra and omit .. material information about the risks associated with Kaletra,” the FDA wrote in a letter that was dated Oct. 29 and posted on the agency’s Web site. Officials at Abbott did not immediately return calls seeking comment. No evidence of long-term benefits The FDA said both promotions implied Kaletra could help patients with HIV, which causes AIDS, stay healthy for five years. Each ad featured pictures of a man looking healthy and captions indicating the images were taken over a four- or five-year period. Text on the ads asked “Where do you see yourself in five years?” and urged patients to discuss Kaletra with their doctors. www.msnbc.com/news/AIDS_front.asp ___________ COMMENT. Every day the evidence that Haart medications rather than helping people are the REAL cause of immune suppression and death. Even the CDC now admits that 48.2% of ALL U.S. 'AIDS mortalities' are really from medication side effects like liver failure and heart disease. Our forum: - http://groups.msn.com/HAARTisHeartless provides the vast amount of evidence of this crime against humanity. >Two HIV drug ads misleading, says FDA > >Promotions for Kaletra omit life-threatening safety risks This doesn't mean the drug doesn't work--just that Abbott is a lying bunch of sh.ts. As far as toxicities go? You bet! They can be terrible. I've known very few people who had no trouble at all--ever. A lot that did fine with few problems. But almost everyone has some trouble. They're toxic. We need better treatments. But they WORK better than NO treatment. No treatment means AIDS and death, as millions around the world have discovered. The pharmaceutical industry and the US Trade Representative under the guidance and encouragement of the US government and George W. Bush have done their level best to assure NO one ever access the very low cost generic medications. Meaning millions suffer and die needlessly. That, to my mind, is genocide. So you're right that the industry has a lot to account for--but you miss the very worst of what they do. George M. Carter "Abbott is a lying bunch of sh.ts." As are all the others and the CDC. Drugs do work....they kill you. |
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