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Medical Forum / Diseases and Disorders / AIDS / October 2004

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Moist internal surfaces

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PaulKing - 26 Oct 2004 21:46 GMT
"According to the A m e r i c a n Academy of A l l e rg y, Asthma &
Immunology (AAAAI), the greatest danger of severe reactions occurs when
latex comes in contact with moist areas of the body or internal
surfaces."
GMCarter - 27 Oct 2004 10:05 GMT
>"According to the A m e r i c a n Academy of A l l e rg y, Asthma &
>Immunology (AAAAI), the greatest danger of severe reactions occurs when
>latex comes in contact with moist areas of the body or internal
>surfaces."

But not from using condoms.

        George M. Carter

**
Chen FC, Buscher U, Niggemann B. Condoms are not a risk factor for
sensitization to latex. Contraception. 2002 Dec;66(6):439-441.

Department of Obstetrics, Charite, Campus Virchow-Clinic of
Humboldt-University, Berlin, Germany.

The study was conducted to assess the prevalence of sensitization to
latex in a group of women with a high risk for atopy and to determine
whether the use of condoms is a relevant risk factor. In a prospective
study, 100 atopic women (defined as having specific IgE to common
aero- or nutritional allergens) were screened for specific IgE
antibodies to latex after delivery: Ten of the 100 women (10%) showed
specific IgE to latex. Total IgE concentrations were higher with a
history of occupational exposure or of symptoms after contact with
latex (p < 0.05, and p < 0.005, respectively), but condom users were
not significantly more frequent in the latex-positive group. Our
results indicate that prior use of condoms does not appear to be a
specific risk factor for sensitization to latex in post-partum women
at high-risk for atopy. Latex-free condoms should only be recommended
to women already known to be sensitized to latex. Copyright 2002
Elsevier Science Inc.
PaulKing - 27 Oct 2004 21:13 GMT
What has this to do with my quote?

The report does not make sense, however. Latex is latex and it makes no
difference if it is shaped like a glove or a condom.

This study smacks of an industry white wash that defies all common sense
and logic. How could you possibly tell where the build-up of IgE came
from?

Think about it. This is pure nonsense.
GMCarter - 28 Oct 2004 12:01 GMT
>What has this to do with my quote?
>
>The report does not make sense, however. Latex is latex and it makes no
>difference if it is shaped like a glove or a condom.

It's not the shape. It's the surface area. The frequency of use. Rate
of exposure. And the very tiny number of people with allergies can use
plastic.

mountain out of a molehill.

        George M. Carter
PaulKing - 27 Oct 2004 22:04 GMT
http://www.families-first.com/features/ovariancancer.htm
One or more of the following characteristics puts you at above average
risk
of ovarian cancer:
Family history of ovarian cancer, breast cancer, colon cancer.
Personal history of breast cancer, endometrial cancer, colon cancer.
No pregnancies or no birth control use and infertility (uninterrupted
ovulation).
Exposure to talc or asbestos (industrial contamination, frequently used
douches, CONDOMS, dusting powder containing talc, used in the genital
area.
Increasing age.
Breast-Ovarian Cancer Syndrome(s)
Ashkenazi Jewish population.
Fertility drugs taken for more than three cycles has been linked to an
increased risk.
GMCarter - 28 Oct 2004 12:14 GMT
>http://www.families-first.com/features/ovariancancer.htm
>One or more of the following characteristics puts you at above average
>risk of ovarian cancer:

Interesting and overall irrelevant. Risk, benefit, dear. The risk for
a woman developing fibrosis from talc on condoms (and what evidence is
that it is still used?) is very limited and the OR relatively low. The
absolute risk is probably nonexistent.

Versus the risk of HIV, STDs, unwanted pregnancy.

        George M. Carter

**
http://www3.interscience.wiley.com/cgi-bin/abstract/73502962/ABSTRACT
Original Article
Perineal talc exposure and risk of ovarian carcinoma
Stella Chang, B.A., Harvey A. Risch, M.D., Ph.D. *
Department of Epidemiology and Public Health, Yale University School
of Medicine, New Haven, Connecticut


*Correspondence to Harvey A. Risch, Department of Epidemiology and
Public Health, Yale University School of Medicine, 60 College Street,
P.O. Box 208034, New Haven, CT 06520-8034

Funded by:
National Health Research and Development Program of Health Canada,
awarded to Dr. Risch; Grant Number: 6613-1415-53

Keywords
case-control studies; ovarian neoplasms; risk factors; talc

Abstract

BACKGROUND
Clinical and epidemiologic studies have indicated the possible
existence of an association between ovarian carcinoma and talcum
powder use. Talc particles have been detected in histologic sections
of ovarian carcinomas. It has also been demonstrated that inert
particles travel from the perineum to the ovaries. Results from
epidemiologic investigations have varied, from risks increased by
twofold to no significant risk detected.

METHODS
A total of 450 patients with borderline and invasive ovarian carcinoma
and 564 population controls in metropolitan Toronto and nearby areas
of southern Ontario, Canada, were identified. These subjects were
interviewed about their reproductive and menstrual histories as well
as their exposure to dusting powders. Continuous unconditional
logistic regression methods were used for analysis.

RESULTS
Exposure to talc, via sanitary napkins, direct application to the
perineum, or both, was significantly associated with risk of ovarian
carcinoma (odds ratio [OR] 1.42, 95% confidence interval [CI]
1.08-1.86). A borderline-significant association was detected between
duration of talc exposure and risk (OR 1.09, 95% CI 0.98-1.21, per 10
years of exposure). No significant association was found between
frequency of exposure and risk. In comparing invasive and borderline
carcinomas, risk remained elevated for both carcinoma types. Only risk
for invasive carcinoma was statistically significant.

CONCLUSIONS
This investigation supports previous contentions that exposure to talc
may increase risk of ovarian carcinoma. Questionable trends in
duration and frequency of exposure suggest that further studies may be
needed to clarify the role of talc in the etiology of this disease.
Cancer 1997; 79:2396-401. © 1997 American Cancer Society.

--------------------------------------------------------------------------------
Received: 23 October 1996; Revised: 31 January 1996; Accepted: 31
January 1996
PaulKing - 28 Oct 2004 21:53 GMT
"Interesting and overall irrelevant."

To you. Perhaps it is because you are not at risk for ovarian cancer.
GMCarter - 29 Oct 2004 10:34 GMT
>"Interesting and overall irrelevant."
>
>To you. Perhaps it is because you are not at risk for ovarian cancer.

Most women (read >99%)  are not at risk from ovarian cancer from male
partners using a condom. Unless you have data to the contrary?

        George M. Carter
PaulKing - 29 Oct 2004 23:44 GMT
"Most women (read >99%)  are not at risk from ovarian cancer from male
partners using a condom. Unless you have data to the contrary?"

How many times do I have to post it?

Where do you get your figure of 99%.

Did you just make it up?
PaulKing - 30 Oct 2004 00:01 GMT
Dear Mr. Carter,

How could you possibly calculate the risk from a carcinogen?

Without a real study, all one can say is that a 'potent carcinogen' or
should I say at least three, being rubbed into the moist tissue of a
woman's sexual organs is not a good idea.

Add to that a teratogen and you have something potentially very serious.

You can make-up any figure you like but the truth is this could be VERY
serious and deserves further study.

I am sure as it is not called 'AIDS that' you will not agree.
GMCarter - 30 Oct 2004 11:22 GMT
>Dear Mr. Carter,
>
>How could you possibly calculate the risk from a carcinogen?

Good question. It's been done! Risks from carcinogen exposure relate
to the frequency and concentration of the exposure, among other
factors. With condoms, your hysterical squealings are virtually
irrelevant compared to other risks we face daily from exposure to a
range of carcinogens.

Meanwhile, the risks associated with HIV, STDs, and/or unwanted
pregnancy make condom use extremely sensible. Of course, not having
sex can be an effective method as well.

        George M. Carter
PaulKing - 31 Oct 2004 04:49 GMT
"With condoms, your hysterical squealings are virtually
irrelevant compared to other risks we face daily from exposure to a range
of carcinogens."

Oh yes. Using a 'potent carcinogen' internally is so very safe. Let's all
rub carcinogens on our dicks just for fun.

You go first......as the only real 'dick' around here.
 
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